C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014852 Adamts13 10090 + 2:26973416-27009628 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014996 Adamts13-002 26973416-26998580 protein_coding
  ENSMUST00000102891 Adamts13-001 26973493-27009628 protein_coding
  ENSMUST00000147216 Adamts13-003 27006571-27009445 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000014996ENSMUST00000102891ENSMUST00000147216
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000014996 0.019±0.01 0.023±0.01 0.044±0.00 0.275±0.27 0.310±0.20 0.331±0.05 0.011±0.01 0.051±0.01 2.001±0.64 0.129±0.04 0.034±0.00 0.054±0.03 0.324±0.22 0.013±0.00
ENSMUST00000102891 N/A N/A 0.006±0.00 0.012±0.01 0.096±0.07 0.378±0.00 N/A 0.099±0.03 1.173±0.82 0.165±0.05 N/A 0.056±0.03 0.155±0.00 0.031±0.00
ENSMUST00000147216 N/A N/A N/A 0.440±0.40 N/A N/A N/A 0.361±0.11 N/A N/A 0.127±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DF CIL_0006DF_0002 CGP 2:26953563-27009628
CIL_0006DA CIL_0006DA_0002 CGP 2:26973416-27021089

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006508 IDA proteolysis
GO:0007596 IEA blood coagulation
GO:0008233 IEA peptidase activity
GO:0008270 IEA zinc ion binding
GO:0009636 IEA response to toxic substance
GO:0034341 IEA response to interferon-gamma
GO:0034612 IEA response to tumor necrosis factor
GO:0043171 IEA peptide catabolic process
GO:0070670 IEA response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076270 adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 protein_coding Danio_rerio
ENSG00000160323 ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 protein_coding Homo_sapiens

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