C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GATA binding protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000170089 Gata2-202 ENSMUSG00000015053 10090 + 6:88193891-88207030 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000170089
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000170089 7.141±6.48 3.614±1.04 5.233±1.09 1.586±1.14 0.597±0.20 0.199±0.00 1.276±0.18 1.214±0.21 0.260±0.13 8.018±1.99 0.643±0.00 5.719±2.48 28.574±21.02 5.138±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001158 ISO enhancer sequence-specific DNA binding
GO:0001655 IMP urogenital system development
GO:0001709 IDA cell fate determination
GO:0001892 IMP embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0008270 IEA zinc ion binding
GO:0021514 IMP ventral spinal cord interneuron differentiation
GO:0021533 IMP cell differentiation in hindbrain
GO:0021902 IMP commitment of neuronal cell to specific neuron type in forebrain
GO:0021954 IMP central nervous system neuron development
GO:0021983 IMP pituitary gland development
GO:0030154 IMP cell differentiation
GO:0030182 IMP neuron differentiation
GO:0035019 IMP somatic stem cell maintenance
GO:0035065 IDA regulation of histone acetylation
GO:0042472 IMP inner ear morphogenesis
GO:0043234 IDA protein complex
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045638 IMP negative regulation of myeloid cell differentiation
GO:0045648 IDA positive regulation of erythrocyte differentiation
GO:0045650 IDA negative regulation of macrophage differentiation
GO:0045654 IDA positive regulation of megakaryocyte differentiation
GO:0045766 IMP positive regulation of angiogenesis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IMP cell maturation
GO:0048663 IMP neuron fate commitment
GO:0048873 IMP homeostasis of number of cells within a tissue
GO:0050766 ISS positive regulation of phagocytosis
GO:0060216 IMP definitive hemopoiesis
GO:0060872 IMP semicircular canal development
GO:0097154 IMP GABAergic neuron differentiation
GO:2000178 IMP negative regulation of neural precursor cell proliferation
GO:2000977 IMP regulation of forebrain neuron differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000082425 gata2a-001 protein_coding Danio_rerio 0 381
ENSDART00000136311 gata2a-002 processed_transcript Danio_rerio 0 357
ENSDART00000082420 gata2a-201 protein_coding Danio_rerio 0 350
ENST00000341105 GATA2-001 protein_coding Homo_sapiens 0 1881
ENST00000430265 GATA2-003 protein_coding Homo_sapiens 0 1273
ENST00000487848 GATA2-002 protein_coding Homo_sapiens 0 1877
ENST00000489987 GATA2-005 processed_transcript Homo_sapiens 0 608

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