C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neutrophil cytosolic factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015950 Ncf1 10090 - 5:134220053-134229625 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016094 Ncf1-002 134220260-134229625 protein_coding
  ENSMUST00000111275 Ncf1-001 134220260-134229625 protein_coding
  ENSMUST00000126934 Ncf1-006 134225717-134227810 retained_intron
  ENSMUST00000139249 Ncf1-005 134223445-134228399 retained_intron
  ENSMUST00000144086 Ncf1-003 134220260-134229625 protein_coding
  ENSMUST00000146354 Ncf1-004 134220053-134229625 nonsense_mediated_decay
  ENSMUST00000182626 Ncf1-007 134221372-134222222 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000016094ENSMUST00000111275ENSMUST00000146354
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000016094 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.339±0.00
ENSMUST00000111275 7.787±2.30 3.727±1.01 4.966±0.13 16.411±6.91 4.079±1.16 1.732±0.54 1.886±0.78 9.246±12.45 14.468±1.06 1.142±0.74 3.489±0.89 0.953±0.48 N/A
ENSMUST00000146354 N/A 4.038±0.95 N/A 10.095±0.00 3.176±0.00 N/A N/A 5.784±3.16 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051K CIL_00051K_0002 CGP 5:134148054-134224355

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001878 IMP response to yeast
GO:0001909 IMP leukocyte mediated cytotoxicity
GO:0002679 IMP respiratory burst involved in defense response
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005791 IEA rough endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 ISA cytosol
GO:0005886 IEA plasma membrane
GO:0006612 IEA protein targeting to membrane
GO:0006691 IMP leukotriene metabolic process
GO:0006742 ISA NADP catabolic process
GO:0006915 IEA apoptotic process
GO:0006954 IMP inflammatory response
GO:0006968 IMP cellular defense response
GO:0008283 IMP cell proliferation
GO:0009617 IMP response to bacterium
GO:0016020 IEA membrane
GO:0016175 ISA superoxide-generating NADPH oxidase activity
GO:0017124 IEA SH3 domain binding
GO:0019898 IEA extrinsic component of membrane
GO:0030425 IEA dendrite
GO:0035091 ISS phosphatidylinositol binding
GO:0042554 IMP superoxide anion generation
GO:0042742 IMP defense response to bacterium
GO:0043020 IEA NADPH oxidase complex
GO:0043025 IEA neuronal cell body
GO:0043325 IEA phosphatidylinositol-3,4-bisphosphate binding
GO:0045730 IMP respiratory burst
GO:0045986 IMP negative regulation of smooth muscle contraction
GO:0050665 IMP hydrogen peroxide biosynthetic process
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0050832 IMP defense response to fungus
GO:0055114 IEA oxidation-reduction process
GO:0070946 IMP neutrophil mediated killing of gram-positive bacterium
GO:0070947 IMP neutrophil mediated killing of fungus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033735 ncf1 neutrophil cytosolic factor 1 protein_coding Danio_rerio
ENSG00000158517 NCF1 neutrophil cytosolic factor 1 protein_coding Homo_sapiens

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