C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neutrophil cytosolic factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000146354 Ncf1-004 ENSMUSG00000015950 10090 - 5:134220053-134229625 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonLiverENSMUST00000146354
Transcript ID Adrenal Breast Colon Liver
ENSMUST00000146354 4.038±0.95 10.095±0.00 3.176±0.00 5.784±3.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051K CIL_00051K_0002 CGP 5:134148054-134224355

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001878 IMP response to yeast
GO:0001909 IMP leukocyte mediated cytotoxicity
GO:0002679 IMP respiratory burst involved in defense response
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 ISA cytosol
GO:0006612 ISS protein targeting to membrane
GO:0006691 IMP leukotriene metabolic process
GO:0006742 ISA NADP catabolic process
GO:0006954 IMP inflammatory response
GO:0006968 IMP cellular defense response
GO:0008283 IMP cell proliferation
GO:0009617 IMP response to bacterium
GO:0016175 ISA superoxide-generating NADPH oxidase activity
GO:0019898 ISS extrinsic component of membrane
GO:0035091 ISS phosphatidylinositol binding
GO:0042554 IMP superoxide anion generation
GO:0042742 IMP defense response to bacterium
GO:0043020 ISS NADPH oxidase complex
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0045730 IMP respiratory burst
GO:0045986 IMP negative regulation of smooth muscle contraction
GO:0050665 IMP hydrogen peroxide biosynthetic process
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0050832 IMP defense response to fungus
GO:0055114 IEA oxidation-reduction process
GO:0070946 IMP neutrophil mediated killing of gram-positive bacterium
GO:0070947 IMP neutrophil mediated killing of fungus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000289473 NCF1-001 protein_coding Homo_sapiens 0 963
ENST00000398421 NCF1-002 retained_intron Homo_sapiens 0 213
ENST00000423083 NCF1B-003 processed_transcript Homo_sapiens 0 200
ENST00000432102 NCF1B-002 processed_transcript Homo_sapiens 0 508
ENST00000433458 NCF1-014 protein_coding Homo_sapiens 0 283
ENST00000435988 NCF1B-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 568
ENST00000438106 NCF1-015 processed_transcript Homo_sapiens 0 329
ENST00000438382 NCF1C-001 unprocessed_pseudogene Homo_sapiens 0 950
ENST00000442021 NCF1-011 protein_coding Homo_sapiens 2e-22 110
ENST00000443956 NCF1-003 processed_transcript Homo_sapiens 1e-22 111
ENST00000449343 NCF1-007 retained_intron Homo_sapiens 0 527
ENST00000455062 NCF1-009 retained_intron Homo_sapiens 2e-21 108
ENST00000464878 NCF1-016 nonsense_mediated_decay Homo_sapiens 1e-21 108

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