C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, L type, alpha 1D subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015968 Cacna1d 10090 - 14:30039949-30491156 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000112249 Cacna1d-201 30039949-30353486 protein_coding
  ENSMUST00000112250 Cacna1d-202 30039949-30491156 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartLungMuscleOvaryPlacentaTestisENSMUST00000112249ENSMUST00000112250
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Lung Muscle Ovary Placenta Testis
ENSMUST00000112249 3.294±0.00 0.885±0.10 0.175±0.03 3.399±0.95 2.298±0.00 0.500±0.15 2.459±1.44 0.072±0.01 3.344±2.12 N/A N/A
ENSMUST00000112250 0.632±0.02 N/A 0.471±0.09 4.471±0.00 2.564±0.38 0.237±0.00 N/A 0.054±0.03 2.476±1.09 1.271±0.00 2.019±0.67

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IEA voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0005891 TAS voltage-gated calcium channel complex
GO:0006816 IEA calcium ion transport
GO:0007188 IMP adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007605 IMP sensory perception of sound
GO:0008331 IDA high voltage-gated calcium channel activity
GO:0030018 IDA Z disc
GO:0030506 IPI ankyrin binding
GO:0046872 IEA metal ion binding
GO:0051393 IEA alpha-actinin binding
GO:0051928 IEA positive regulation of calcium ion transport
GO:0060372 IMP regulation of atrial cardiac muscle cell membrane repolarization
GO:0070509 IBA calcium ion import
GO:0070588 IMP calcium ion transmembrane transport
GO:0086046 IMP membrane depolarization during SA node cell action potential
GO:0086052 IEA membrane repolarization during SA node cell action potential
GO:0086059 IMP voltage-gated calcium channel activity involved SA node cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901016 IMP regulation of potassium ion transmembrane transporter activity
GO:1901379 IMP regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024004 cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a protein_coding Danio_rerio
ENSG00000157388 CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit protein_coding Homo_sapiens

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