C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vitronectin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017344 Vtn 10090 + 11:78499091-78502324 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017488 Vtn-001 78499120-78502324 protein_coding
  ENSMUST00000128479 Vtn-002 78499091-78500585 retained_intron
  ENSMUST00000146997 Vtn-003 78499172-78500244 retained_intron
  ENSMUST00000153628 Vtn-004 78500606-78502222 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017488ENSMUST00000128479ENSMUST00000146997ENSMUST00000153628
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017488 10.546±2.67 1.130±0.32 1.447±0.03 24.955±7.58 15.916±1.88 1.905±0.69 15.829±1.38 1.121±0.44 982.967±518.44 11.959±0.51 7.488±1.57 2.652±1.30 13.116±14.90 0.319±0.08
ENSMUST00000128479 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.483±0.22 N/A
ENSMUST00000146997 N/A 0.607±0.24 N/A N/A N/A N/A N/A 0.571±0.00 N/A N/A N/A 3.335±0.79 N/A 0.247±0.00
ENSMUST00000153628 N/A N/A N/A 8.706±0.00 6.052±0.00 1.389±0.00 5.733±0.00 0.984±0.40 N/A N/A N/A 1.653±0.35 N/A 0.232±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FM CIL_0000FM_0003 CGP 11:78472330-78502324

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005044 IEA scavenger receptor activity
GO:0005178 IEA integrin binding
GO:0005515 IEA protein binding
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0006898 IEA receptor-mediated endocytosis
GO:0006955 IEA immune response
GO:0007160 IDA cell-matrix adhesion
GO:0008201 IEA heparin binding
GO:0010811 IDA positive regulation of cell-substrate adhesion
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0030198 IDA extracellular matrix organization
GO:0030247 IEA polysaccharide binding
GO:0031012 IEA extracellular matrix
GO:0032092 IEA positive regulation of protein binding
GO:0033627 IEA cell adhesion mediated by integrin
GO:0035987 IEA endodermal cell differentiation
GO:0048260 IEA positive regulation of receptor-mediated endocytosis
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050840 IDA extracellular matrix binding
GO:0061302 IEA smooth muscle cell-matrix adhesion
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053831 vtnb vitronectin b protein_coding Danio_rerio
ENSDARG00000055388 vtna vitronectin a protein_coding Danio_rerio
ENSG00000109072 VTN vitronectin protein_coding Homo_sapiens

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