C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vitronectin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109072 VTN 9606 - 17:28367276-28373091 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000226218 VTN-001 28367276-28370822 protein_coding
  ENST00000539746 VTN-004 28367868-28368937 retained_intron
  ENST00000542029 VTN-003 28369682-28373091 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyOvaryTestisENST00000226218ENST00000542029
Transcript ID Breast Heart Kidney Ovary Testis
ENST00000226218 2.422±0.00 10.513±9.09 303.476±0.00 9.793±0.00 7.286±0.00
ENST00000542029 N/A 3.568±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FM CIL_0000FM_0002 CGP 17:28364356-28404049

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005044 IEA scavenger receptor activity
GO:0005178 IDA integrin binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006898 IEA receptor-mediated endocytosis
GO:0006955 IEA:TAS immune response
GO:0007155 TAS cell adhesion
GO:0007160 IDA cell-matrix adhesion
GO:0008201 IEA heparin binding
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0010951 IDA negative regulation of endopeptidase activity
GO:0014911 IDA positive regulation of smooth muscle cell migration
GO:0030195 IC negative regulation of blood coagulation
GO:0030198 TAS extracellular matrix organization
GO:0030247 IEA polysaccharide binding
GO:0030449 TAS regulation of complement activation
GO:0030949 TAS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031012 IDA extracellular matrix
GO:0032092 IDA positive regulation of protein binding
GO:0033627 IDA cell adhesion mediated by integrin
GO:0035987 IDA endodermal cell differentiation
GO:0045087 TAS innate immune response
GO:0048260 IDA positive regulation of receptor-mediated endocytosis
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050840 IEA extracellular matrix binding
GO:0061302 IDA smooth muscle cell-matrix adhesion
GO:0070062 IDA extracellular vesicular exosome
GO:0071062 TAS alphav-beta3 integrin-vitronectin complex
GO:0072562 IDA blood microparticle
GO:0090303 IC positive regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053831 vtnb vitronectin b protein_coding Danio_rerio
ENSDARG00000055388 vtna vitronectin a protein_coding Danio_rerio
ENSMUSG00000017344 Vtn vitronectin protein_coding Mus_musculus

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