C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-crk sarcoma virus CT10 oncogene homolog (avian)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000017920 Crk-001 ENSMUSG00000017776 10090 + 11:75679259-75706065 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017920
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017920 23.955±2.89 17.889±2.82 30.865±7.46 23.335±8.31 20.010±3.54 20.525±4.78 18.747±2.23 23.316±1.50 14.955±2.98 27.778±2.85 8.304±4.45 22.663±5.30 34.065±10.36 3.279±2.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000034 CIL_000034_0002 CGP 11:75679259-75765845

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 IPI SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0009967 IPI positive regulation of signal transduction
GO:0015629 IDA actin cytoskeleton
GO:0019904 IEA protein domain specific binding
GO:0030674 IEA protein binding, bridging
GO:0032319 ISS regulation of Rho GTPase activity
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0035020 IEA regulation of Rac protein signal transduction
GO:0042169 IEA SH2 domain binding
GO:0045309 IDA protein phosphorylated amino acid binding
GO:0046875 IPI ephrin receptor binding
GO:0048013 ISS ephrin receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000300574 CRK-001 protein_coding Homo_sapiens 0 2326
ENST00000398970 CRK-002 protein_coding Homo_sapiens 0 1059
ENST00000571520 CTD-2545G14.2-001 processed_pseudogene Homo_sapiens 1.4013e-45 185
ENST00000572145 CRK-004 processed_transcript Homo_sapiens 0 582
ENST00000574295 CRK-003 protein_coding Homo_sapiens 0 638

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