C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DEXH (Asp-Glu-X-His) box polypeptide 58
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017830 Dhx58 10090 - 11:100694884-100704271 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017974 Dhx58-001 100694884-100704271 protein_coding
  ENSMUST00000126167 Dhx58-003 100701392-100704253 processed_transcript
  ENSMUST00000132930 Dhx58-002 100702760-100704271 processed_transcript
  ENSMUST00000140543 Dhx58-006 100695063-100696620 processed_transcript
  ENSMUST00000149869 Dhx58-005 100695253-100699235 processed_transcript
  ENSMUST00000150656 Dhx58-004 100702148-100703347 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017974ENSMUST00000126167ENSMUST00000132930ENSMUST00000140543ENSMUST00000149869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017974 5.159±1.57 10.505±3.34 2.325±0.38 0.678±0.16 4.581±1.47 3.852±0.72 0.494±0.24 1.536±0.51 4.241±2.32 3.583±0.59 0.261±0.13 3.178±1.41 1.376±0.09 11.896±4.07
ENSMUST00000126167 N/A N/A N/A 0.874±0.00 N/A N/A N/A 0.660±0.00 N/A N/A 0.349±0.00 2.426±0.00 6.233±0.18 16.626±0.00
ENSMUST00000132930 N/A N/A N/A N/A 2.063±0.00 N/A 0.451±0.00 0.520±0.00 N/A N/A 0.077±0.00 2.053±0.00 N/A N/A
ENSMUST00000140543 N/A N/A N/A 0.206±0.00 N/A N/A N/A N/A N/A N/A 0.161±0.00 1.384±0.00 N/A N/A
ENSMUST00000149869 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.174±0.02 N/A N/A 18.044±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003J CIL_00003J_0002 CGP 11:100627543-100704271
CIL_0004GH CIL_0004GH_0002 CGP 11:100694884-100712465

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003725 ISS double-stranded RNA binding
GO:0003727 ISS single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0008152 IEA metabolic process
GO:0008270 ISS zinc ion binding
GO:0009615 IMP response to virus
GO:0032480 IMP negative regulation of type I interferon production
GO:0032481 IMP positive regulation of type I interferon production
GO:0039534 ISS negative regulation of MDA-5 signaling pathway
GO:0039536 IMP negative regulation of RIG-I signaling pathway
GO:0045087 IEA innate immune response
GO:0045088 IEA regulation of innate immune response
GO:0045824 IMP negative regulation of innate immune response
GO:0051607 IEA defense response to virus
GO:1900245 IMP positive regulation of MDA-5 signaling pathway
GO:1900246 IMP positive regulation of RIG-I signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089463 dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 protein_coding Danio_rerio
ENSG00000108771 DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 protein_coding Homo_sapiens

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