C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018166 Erbb3 10090 - 10:128567523-128589652 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082059 Erbb3-001 128567523-128589652 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082059
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082059 3.889±2.30 0.696±0.23 9.156±1.60 0.530±0.22 10.598±1.42 60.607±6.76 0.721±0.48 14.783±1.82 13.217±10.33 14.661±0.39 0.445±0.28 3.733±1.05 4.870±2.29 0.417±0.33

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003197 IMP endocardial cushion development
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0007162 IEA negative regulation of cell adhesion
GO:0007165 IEA signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007422 IMP peripheral nervous system development
GO:0009968 IEA negative regulation of signal transduction
GO:0014037 IMP Schwann cell differentiation
GO:0014065 IEA phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019838 IEA growth factor binding
GO:0021545 IMP cranial nerve development
GO:0023014 IEA signal transduction by phosphorylation
GO:0030296 IEA protein tyrosine kinase activator activity
GO:0042127 IEA regulation of cell proliferation
GO:0042802 IEA identical protein binding
GO:0043235 ISO receptor complex
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0046982 IEA protein heterodimerization activity
GO:0051048 IEA negative regulation of secretion
GO:0051402 IEA neuron apoptotic process
GO:0061098 IEA positive regulation of protein tyrosine kinase activity
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006202 erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a protein_coding Danio_rerio
ENSDARG00000036993 erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b protein_coding Danio_rerio
ENSG00000065361 ERBB3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 protein_coding Homo_sapiens

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