C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000082059 Erbb3-001 ENSMUSG00000018166 10090 - 10:128567523-128589652 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082059
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082059 3.889±2.30 0.696±0.23 9.156±1.60 0.530±0.22 10.598±1.42 60.607±6.76 0.721±0.48 14.783±1.82 13.217±10.33 14.661±0.39 0.445±0.28 3.733±1.05 4.870±2.29 0.417±0.33

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003197 IMP endocardial cushion development
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0007162 IEA negative regulation of cell adhesion
GO:0007165 IEA signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007422 IMP peripheral nervous system development
GO:0009968 IEA negative regulation of signal transduction
GO:0014037 IMP Schwann cell differentiation
GO:0014065 IEA phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019838 IEA growth factor binding
GO:0021545 IMP cranial nerve development
GO:0023014 IEA signal transduction by phosphorylation
GO:0030296 IEA protein tyrosine kinase activator activity
GO:0042127 IEA regulation of cell proliferation
GO:0042802 IEA identical protein binding
GO:0043235 ISO receptor complex
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0046982 IEA protein heterodimerization activity
GO:0051048 IEA negative regulation of secretion
GO:0051402 IEA neuron apoptotic process
GO:0061098 IEA positive regulation of protein tyrosine kinase activity
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000014892 erbb3a-201 protein_coding Danio_rerio 0 261
ENSDART00000148908 erbb3a-001 protein_coding Danio_rerio 0 261
ENSDART00000092118 erbb4a-002 protein_coding Danio_rerio 4e-39 169
ENSDART00000145822 erbb4a-001 protein_coding Danio_rerio 4e-39 169
ENSDART00000079483 ERBB4 (3 of 3)-201 protein_coding Danio_rerio 2e-36 159
ENST00000267101 ERBB3-001 protein_coding Homo_sapiens 0 4717
ENST00000411731 ERBB3-006 protein_coding Homo_sapiens 0 606
ENST00000415288 ERBB3-024 protein_coding Homo_sapiens 0 4458
ENST00000546884 ERBB3-022 retained_intron Homo_sapiens 0 706
ENST00000548709 ERBB3-018 retained_intron Homo_sapiens 0 604
ENST00000549061 ERBB3-011 protein_coding Homo_sapiens 0 599
ENST00000549205 ERBB3-016 retained_intron Homo_sapiens 0 307
ENST00000549282 ERBB3-010 protein_coding Homo_sapiens 0 521
ENST00000549472 ERBB3-026 retained_intron Homo_sapiens 0 219
ENST00000549672 ERBB3-020 protein_coding Homo_sapiens 0 532
ENST00000549832 ERBB3-004 protein_coding Homo_sapiens 0 1506
ENST00000550070 ERBB3-009 protein_coding Homo_sapiens 0 1633
ENST00000550828 ERBB3-025 protein_coding Homo_sapiens 0 211
ENST00000551085 ERBB3-023 nonsense_mediated_decay Homo_sapiens 0 3201
ENST00000551242 ERBB3-003 nonsense_mediated_decay Homo_sapiens 0 1208
ENST00000553131 ERBB3-005 protein_coding Homo_sapiens 0 2318

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