C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kinase suppressor of ras 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018478 Ksr1-001 ENSMUSG00000018334 10090 - 11:79013440-79146407 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000018478
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000018478 10.301±0.90 3.773±1.26 5.211±0.52 2.776±0.87 8.389±1.13 5.270±1.05 2.301±0.16 2.378±0.78 0.931±0.97 6.945±1.13 14.585±6.40 3.735±1.26 0.439±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SM CIL_0007SM_0002 VISTA 11:78750979-79355443
CIL_0006M1 CIL_0006M1_0002 CGP 11:78962974-79146407
CIL_0001AY CIL_0001AY_0002 CGP 11:79013440-79254671

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005078 IDA MAP-kinase scaffold activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006468 IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0043410 IDA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000268763 KSR1-201 protein_coding Homo_sapiens 0 1491
ENST00000339824 KSR2-001 protein_coding Homo_sapiens 0 398
ENST00000398982 KSR1-011 protein_coding Homo_sapiens 0 1413
ENST00000398988 KSR1-001 protein_coding Homo_sapiens 0 1395
ENST00000425217 KSR2-201 protein_coding Homo_sapiens 0 398
ENST00000509603 KSR1-202 protein_coding Homo_sapiens 0 1395
ENST00000579961 KSR1-002 processed_transcript Homo_sapiens 0 298
ENST00000580430 KSR1-017 protein_coding Homo_sapiens 0 505
ENST00000581975 KSR1-010 processed_transcript Homo_sapiens 0 612
ENST00000582410 KSR1-012 protein_coding Homo_sapiens 0 462
ENST00000583998 KSR1-018 processed_transcript Homo_sapiens 0 331

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