C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine A2b receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018500 Adora2b 10090 + 11:62248984-62266453 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018644 Adora2b-001 62248984-62266453 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018644
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018644 2.430±0.18 1.491±0.30 27.766±7.21 0.661±0.23 3.517±0.79 1.490±0.49 0.682±0.14 3.188±0.86 0.184±0.13 12.487±3.13 0.204±0.09 2.653±1.34 2.292±1.67 0.880±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XH CIL_0002XH_0002 CGP 11:62248984-62281375

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002882 IMP positive regulation of chronic inflammatory response to non-antigenic stimulus
GO:0004930 IMP G-protein coupled receptor activity
GO:0005886 IDA plasma membrane
GO:0007189 IMP adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0010575 IMP positive regulation vascular endothelial growth factor production
GO:0016021 IEA integral component of membrane
GO:0030819 IMP positive regulation of cAMP biosynthetic process
GO:0030828 IMP positive regulation of cGMP biosynthetic process
GO:0031284 IMP positive regulation of guanylate cyclase activity
GO:0031668 IDA cellular response to extracellular stimulus
GO:0032722 IMP positive regulation of chemokine production
GO:0032755 IMP positive regulation of interleukin-6 production
GO:0043306 IMP positive regulation of mast cell degranulation
GO:0060087 IMP relaxation of vascular smooth muscle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002533 adora2b adenosine A2b receptor protein_coding Danio_rerio
ENSG00000170425 ADORA2B adenosine A2b receptor protein_coding Homo_sapiens

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