C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenosine A2b receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018644 Adora2b-001 ENSMUSG00000018500 10090 + 11:62248984-62266453 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018644
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018644 2.430±0.18 1.491±0.30 27.766±7.21 0.661±0.23 3.517±0.79 1.490±0.49 0.682±0.14 3.188±0.86 0.184±0.13 12.487±3.13 0.204±0.09 2.653±1.34 2.292±1.67 0.880±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XH CIL_0002XH_0002 CGP 11:62248984-62281375

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002882 IMP positive regulation of chronic inflammatory response to non-antigenic stimulus
GO:0004930 IMP G-protein coupled receptor activity
GO:0005886 IDA plasma membrane
GO:0007189 IMP adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0010575 IMP positive regulation vascular endothelial growth factor production
GO:0016021 IEA integral component of membrane
GO:0030819 IMP positive regulation of cAMP biosynthetic process
GO:0030828 IMP positive regulation of cGMP biosynthetic process
GO:0031284 IMP positive regulation of guanylate cyclase activity
GO:0031668 IDA cellular response to extracellular stimulus
GO:0032722 IMP positive regulation of chemokine production
GO:0032755 IMP positive regulation of interleukin-6 production
GO:0043306 IMP positive regulation of mast cell degranulation
GO:0060087 IMP relaxation of vascular smooth muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000304222 ADORA2B-001 protein_coding Homo_sapiens 0 1332
ENST00000337539 ADORA2A-001 protein_coding Homo_sapiens 0 200
ENST00000358654 SPECC1L-ADORA2A-001 nonsense_mediated_decay Homo_sapiens 0 200
ENST00000424232 ADORA2A-003 protein_coding Homo_sapiens 7e-32 141
ENST00000429195 ADORA2BP1-001 processed_pseudogene Homo_sapiens 0 558
ENST00000439591 ADORA2A-012 protein_coding Homo_sapiens 3e-20 102
ENST00000444262 ADORA2A-005 protein_coding Homo_sapiens 0 200
ENST00000486108 ADORA2A-009 protein_coding Homo_sapiens 6e-40 169
ENST00000496258 ADORA2A-002 protein_coding Homo_sapiens 7e-28 128
ENST00000582124 ADORA2B-002 retained_intron Homo_sapiens 0 891
ENST00000610595 SPECC1L-ADORA2A-201 protein_coding Homo_sapiens 0 200
ENST00000611543 SPECC1L-ADORA2A-202 protein_coding Homo_sapiens 0 200
ENST00000618076 SPECC1L-ADORA2A-203 protein_coding Homo_sapiens 0 200

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