C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter, creatine), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019558 Slc6a8 10090 + X:73673150-73682502 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033752 Slc6a8-001 73673150-73682502 protein_coding
  ENSMUST00000114464 Slc6a8-004 73676846-73682502 nonsense_mediated_decay
  ENSMUST00000114465 Slc6a8-002 73673785-73682502 protein_coding
  ENSMUST00000114467 Slc6a8-201 73673242-73681640 protein_coding
  ENSMUST00000146796 Slc6a8-011 73673919-73677325 retained_intron
  ENSMUST00000164449 Slc6a8-006 73673707-73681291 protein_coding
  ENSMUST00000166200 Slc6a8-010 73678878-73679999 processed_transcript
  ENSMUST00000167828 Slc6a8-014 73678893-73680002 retained_intron
  ENSMUST00000168764 Slc6a8-013 73677059-73679768 retained_intron
  ENSMUST00000168831 Slc6a8-003 73673958-73681289 protein_coding
  ENSMUST00000170574 Slc6a8-015 73678893-73679915 retained_intron
  ENSMUST00000170614 Slc6a8-009 73678154-73681100 retained_intron
  ENSMUST00000171398 Slc6a8-012 73675507-73677344 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033752ENSMUST00000114464ENSMUST00000114465ENSMUST00000114467ENSMUST00000168831ENSMUST00000170614
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033752 2.669±0.00 13.251±4.57 10.676±0.51 3.499±1.22 5.521±0.46 59.294±19.84 12.106±2.05 26.728±6.85 0.289±0.12 7.279±2.87 8.993±1.47 9.841±2.45 16.073±11.16 N/A
ENSMUST00000114464 N/A N/A 8.226±0.80 9.301±3.42 4.193±0.63 N/A 11.075±0.79 18.302±2.35 0.473±0.20 N/A N/A 7.184±1.04 16.736±9.10 0.422±0.14
ENSMUST00000114465 7.640±3.30 13.229±1.20 10.292±0.38 2.904±0.29 6.390±0.63 58.037±0.00 23.442±8.53 20.816±4.79 0.478±0.19 7.361±0.02 25.847±2.01 4.328±0.00 19.725±19.43 0.928±0.13
ENSMUST00000114467 2.651±0.66 8.995±1.21 N/A 5.881±2.17 5.056±1.82 55.730±14.38 15.572±2.81 27.854±4.06 0.526±0.43 5.706±0.48 N/A 8.124±2.27 9.205±3.53 0.640±0.46
ENSMUST00000168831 N/A N/A N/A N/A N/A N/A N/A N/A 0.421±0.10 N/A N/A 9.496±0.00 8.072±0.00 N/A
ENSMUST00000170614 N/A N/A N/A N/A N/A N/A N/A N/A 0.661±0.10 N/A N/A 10.879±1.38 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UY CIL_0001UY_0002 CGP X:73655994-73682502
CIL_0001UX CIL_0001UX_0002 CGP X:73673150-73716175

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005308 IEA creatine transmembrane transporter activity
GO:0005309 IEA creatine:sodium symporter activity
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005887 IEA integral component of plasma membrane
GO:0006814 IEA sodium ion transport
GO:0006836 IEA neurotransmitter transport
GO:0015220 IEA choline transmembrane transporter activity
GO:0015871 IEA choline transport
GO:0015881 IEA creatine transport
GO:1902598 IEA creatine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043646 slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 protein_coding Danio_rerio
ENSG00000130821 SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 protein_coding Homo_sapiens
ENSG00000273554 AC136616.1 protein_coding Homo_sapiens

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