C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000044306 Grm1-002 ENSMUSG00000019828 10090 - 10:10686059-11082356 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLiverMuscleOvaryPlacentaENSMUST00000044306
Transcript ID Brain Breast Liver Muscle Ovary Placenta
ENSMUST00000044306 0.588±0.25 0.022±0.02 0.005±0.00 0.032±0.01 0.008±0.00 0.009±0.01

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0000187 IDA activation of MAPK activity
GO:0001639 TAS PLC activating G-protein coupled glutamate receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005887 ISS integral component of plasma membrane
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007206 TAS phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
GO:0007216 ISS G-protein coupled glutamate receptor signaling pathway
GO:0007626 IMP locomotory behavior
GO:0008066 ISS glutamate receptor activity
GO:0014069 IDA postsynaptic density
GO:0019233 IMP sensory perception of pain
GO:0030425 IDA dendrite
GO:0038037 IEA G-protein coupled receptor dimeric complex
GO:0038038 IEA G-protein coupled receptor homodimeric complex
GO:0038042 ISS dimeric G-protein coupled receptor signaling pathway
GO:0043005 IDA neuron projection
GO:0043025 TAS neuronal cell body
GO:0043408 IDA regulation of MAPK cascade
GO:0045211 TAS postsynaptic membrane
GO:0051482 ISS positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051930 IDA regulation of sensory perception of pain
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0071257 IMP cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000048546 GRM1 (2 of 2)-201 protein_coding Danio_rerio 0 1389
ENSDART00000030324 grm1a-201 protein_coding Danio_rerio 0 1230
ENSDART00000142653 grm1a-001 protein_coding Danio_rerio 0 1230
ENSDART00000154150 GRM1 (2 of 2)-001 protein_coding Danio_rerio 0 403
ENSDART00000013311 grm6a-201 protein_coding Danio_rerio 3e-16 94
ENSDART00000138993 grm6a-001 protein_coding Danio_rerio 3e-16 94
ENSDART00000012940 GRM2 (2 of 2)-201 protein_coding Danio_rerio 3e-16 94
ENST00000231188 GRM6-201 protein_coding Homo_sapiens 0.0000000000005 82
ENST00000282753 GRM1-001 protein_coding Homo_sapiens 0 4224
ENST00000296479 GRM2-002 nonsense_mediated_decay Homo_sapiens 1e-16 94
ENST00000305432 GRM5-001 protein_coding Homo_sapiens 0 821
ENST00000305447 GRM5-005 protein_coding Homo_sapiens 0 821
ENST00000355289 GRM1-019 protein_coding Homo_sapiens 0 3380
ENST00000361719 GRM1-201 protein_coding Homo_sapiens 0 4224
ENST00000395052 GRM2-001 protein_coding Homo_sapiens 1e-16 94
ENST00000442933 GRM2-005 protein_coding Homo_sapiens 0.000000000008 77
ENST00000455756 GRM5-201 protein_coding Homo_sapiens 0 821
ENST00000464585 GRM2-004 retained_intron Homo_sapiens 3e-16 94
ENST00000475478 GRM2-003 processed_transcript Homo_sapiens 7e-17 94
ENST00000492807 GRM1-002 protein_coding Homo_sapiens 0 3380
ENST00000502405 GRM1-018 retained_intron Homo_sapiens 0 1247
ENST00000507005 GRM1-017 retained_intron Homo_sapiens 0 1247
ENST00000507907 GRM1-020 protein_coding Homo_sapiens 0 3304
ENST00000517717 GRM6-001 protein_coding Homo_sapiens 0.0000000000002 82
ENST00000519003 GRM6-004 retained_intron Homo_sapiens 0.00000000000004 82

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