C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019960 Dusp6 10090 + 10:99263231-99267488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020118 Dusp6-201 99263231-99267488 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020118 18.281±0.61 71.955±3.03 12.034±1.89 8.336±2.47 23.636±7.37 49.582±4.61 8.579±0.95 21.319±2.04 17.915±8.21 49.492±5.54 3.404±0.27 16.984±4.85 5.671±2.94 1.951±0.76

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IEA inactivation of MAPK activity
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0004721 IDA phosphoprotein phosphatase activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006470 IDA protein dephosphorylation
GO:0008138 IBA protein tyrosine/serine/threonine phosphatase activity
GO:0009953 IBA dorsal/ventral pattern formation
GO:0010033 IEA response to organic substance
GO:0010942 IEA positive regulation of cell death
GO:0014070 IEA response to organic cyclic compound
GO:0030154 IEA cell differentiation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0040036 IBA regulation of fibroblast growth factor receptor signaling pathway
GO:0042493 IEA response to drug
GO:0042663 IBA regulation of endodermal cell fate specification
GO:0043065 IBA positive regulation of apoptotic process
GO:0051409 IEA response to nitrosative stress
GO:0060420 IMP regulation of heart growth
GO:0070373 IBA negative regulation of ERK1 and ERK2 cascade
GO:0070848 IEA response to growth factor

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070914 dusp6 dual specificity phosphatase 6 protein_coding Danio_rerio
ENSG00000139318 DUSP6 dual specificity phosphatase 6 protein_coding Homo_sapiens

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