C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000070914 dusp6 7955 - 25:18813588-18817793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000104496 dusp6-001 18813588-18817793 protein_coding
  ENSDART00000133820 dusp6-002 18814536-18815447 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000104496
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000104496 36.476±8.04 64.524±39.56 21.378±0.00 2.133±0.00 61.949±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000213 CIL_000213_0001 CGP 25:18813588-18922771

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IBA inactivation of MAPK activity
GO:0004721 IDA phosphoprotein phosphatase activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005829 IBA cytosol
GO:0006470 IEA protein dephosphorylation
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0009953 IMP dorsal/ventral pattern formation
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016311 IEA dephosphorylation
GO:0016740 IEA transferase activity
GO:0016787 IEA hydrolase activity
GO:0016791 IEA phosphatase activity
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0042663 IGI regulation of endodermal cell fate specification
GO:0043065 IBA positive regulation of apoptotic process
GO:0060420 IBA regulation of heart growth
GO:0070373 IBA negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000139318 DUSP6 dual specificity phosphatase 6 protein_coding Homo_sapiens
ENSMUSG00000019960 Dusp6 dual specificity phosphatase 6 protein_coding Mus_musculus

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