C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptotic peptidase activating factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019979 Apaf1 10090 - 10:90989311-91082770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020157 Apaf1-001 90989318-91082770 protein_coding
  ENSMUST00000159110 Apaf1-002 90989311-91082662 protein_coding
  ENSMUST00000159457 Apaf1-006 90995733-91000411 processed_transcript
  ENSMUST00000160725 Apaf1-008 90989313-90991590 retained_intron
  ENSMUST00000160788 Apaf1-004 91066890-91082770 protein_coding
  ENSMUST00000161095 Apaf1-007 90996740-90999719 retained_intron
  ENSMUST00000161987 Apaf1-005 91065392-91082429 protein_coding
  ENSMUST00000162618 Apaf1-003 90990602-91082704 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020157ENSMUST00000159110ENSMUST00000160788ENSMUST00000161987ENSMUST00000162618
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020157 1.266±0.85 0.872±0.00 0.948±0.10 2.651±1.50 1.787±0.97 2.586±0.68 0.867±0.15 0.843±0.10 1.235±1.04 3.139±1.00 0.265±0.03 1.122±0.40 1.538±0.68 0.581±0.07
ENSMUST00000159110 0.986±0.37 0.940±0.29 0.858±0.37 1.236±0.40 1.716±1.35 1.796±0.41 0.397±0.14 0.276±0.02 1.179±0.64 1.273±0.47 0.283±0.09 1.877±0.87 1.831±0.55 0.301±0.21
ENSMUST00000160788 N/A 1.902±0.76 N/A N/A 2.579±1.07 N/A N/A 0.591±0.00 N/A 2.684±0.00 N/A 2.982±0.34 N/A N/A
ENSMUST00000161987 N/A N/A N/A N/A N/A N/A N/A N/A 0.149±0.00 N/A N/A N/A N/A N/A
ENSMUST00000162618 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.207±0.11 1.264±0.25 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090D CIL_00090D_0002 VISTA 10:90885612-91488565

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275 IMP multicellular organismal development
GO:0007420 IMP brain development
GO:0008635 IBA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 IPI cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0030900 IMP forebrain development
GO:0042802 IPI identical protein binding
GO:0043293 IBA apoptosome
GO:0043531 IEA ADP binding
GO:0051402 IGI neuron apoptotic process
GO:0070062 IEA extracellular vesicular exosome
GO:1902510 IGI regulation of apoptotic DNA fragmentation
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021239 apaf1 apoptotic protease activating factor 1 protein_coding Danio_rerio
ENSG00000120868 APAF1 apoptotic peptidase activating factor 1 protein_coding Homo_sapiens

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