C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: apoptotic peptidase activating factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020157 Apaf1-001 ENSMUSG00000019979 10090 - 10:90989318-91082770 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020157 1.266±0.85 0.872±0.00 0.948±0.10 2.651±1.50 1.787±0.97 2.586±0.68 0.867±0.15 0.843±0.10 1.235±1.04 3.139±1.00 0.265±0.03 1.122±0.40 1.538±0.68 0.581±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090D CIL_00090D_0002 VISTA 10:90885612-91488565

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275 IMP multicellular organismal development
GO:0007420 IMP brain development
GO:0008635 IBA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 IPI cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0030900 IMP forebrain development
GO:0042802 IPI identical protein binding
GO:0043293 IBA apoptosome
GO:0043531 IEA ADP binding
GO:0051402 IGI neuron apoptotic process
GO:0070062 IEA extracellular vesicular exosome
GO:1902510 IGI regulation of apoptotic DNA fragmentation
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000333991 APAF1-201 protein_coding Homo_sapiens 0 959
ENST00000357310 APAF1-202 protein_coding Homo_sapiens 0 2813
ENST00000359972 APAF1-001 protein_coding Homo_sapiens 0 2545
ENST00000546491 APAF1-009 processed_transcript Homo_sapiens 0 593
ENST00000547045 APAF1-005 protein_coding Homo_sapiens 0 2804
ENST00000549007 APAF1-006 protein_coding Homo_sapiens 0 2804
ENST00000550527 APAF1-004 protein_coding Homo_sapiens 0 3976
ENST00000551964 APAF1-002 protein_coding Homo_sapiens 0 4244
ENST00000552268 APAF1-003 protein_coding Homo_sapiens 0 959
ENST00000552929 APAF1-010 processed_transcript Homo_sapiens 0 398
ENST00000555047 APAF1-011 retained_intron Homo_sapiens 0 374

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