C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020263 Appl2 10090 - 10:83600033-83648738 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020500 Appl2-001 83600033-83648738 protein_coding
  ENSMUST00000127788 Appl2-006 83608607-83611102 retained_intron
  ENSMUST00000130285 Appl2-009 83602767-83611881 retained_intron
  ENSMUST00000133719 Appl2-004 83620827-83637443 processed_transcript
  ENSMUST00000141048 Appl2-007 83601904-83603384 retained_intron
  ENSMUST00000146876 Appl2-014 83617419-83648665 protein_coding
  ENSMUST00000147118 Appl2-011 83614259-83628302 processed_transcript
  ENSMUST00000147582 Appl2-002 83605645-83648670 retained_intron
  ENSMUST00000148096 Appl2-010 83602871-83611268 retained_intron
  ENSMUST00000150351 Appl2-012 83605765-83611728 retained_intron
  ENSMUST00000150685 Appl2-005 83620713-83648603 nonsense_mediated_decay
  ENSMUST00000176294 Appl2-003 83624646-83648675 protein_coding
  ENSMUST00000176675 Appl2-013 83600742-83609008 nonsense_mediated_decay
  ENSMUST00000177187 Appl2-008 83600397-83603130 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020500ENSMUST00000130285ENSMUST00000146876ENSMUST00000147582ENSMUST00000176294ENSMUST00000176675
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020500 3.552±1.50 13.475±4.96 6.750±0.54 5.089±3.33 3.131±1.15 12.184±1.77 5.033±1.44 4.873±0.76 2.064±1.06 8.481±1.46 4.960±0.44 8.124±6.39 5.746±2.81 5.420±1.16
ENSMUST00000130285 2.365±0.00 N/A N/A N/A 2.982±0.51 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000146876 N/A 154.584±51.49 N/A N/A 7.855±0.22 31.364±4.96 N/A N/A 2.451±0.37 N/A N/A 10.735±2.82 N/A N/A
ENSMUST00000147582 4.056±1.86 27.979±13.08 4.307±0.04 2.067±0.39 2.352±0.94 15.559±1.41 2.661±0.80 2.244±0.62 1.414±0.86 8.041±0.42 1.384±0.45 8.163±3.31 1.770±0.49 4.444±1.41
ENSMUST00000176294 N/A N/A N/A N/A N/A N/A N/A N/A 3.983±0.44 N/A N/A 11.660±1.86 N/A N/A
ENSMUST00000176675 N/A N/A N/A 24.323±0.00 N/A N/A N/A N/A N/A N/A N/A 51.000±0.00 12.103±6.73 16.027±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004G8 CIL_0004G8_0002 CGP 10:83543941-83648738
CIL_0004G6 CIL_0004G6_0002 CGP 10:83600033-83762761

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 ISS nucleus
GO:0007049 IEA cell cycle
GO:0008283 ISS cell proliferation
GO:0010008 ISS endosome membrane
GO:0016581 ISS NuRD complex
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078139 appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 protein_coding Danio_rerio
ENSG00000136044 APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 protein_coding Homo_sapiens

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