C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: F-box and WD-40 domain protein 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109366 Fbxw11-001 ENSMUSG00000020271 10090 + 11:32642724-32746569 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000109366
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109366 16.971±5.81 30.431±4.51 9.862±0.30 13.228±8.34 23.149±9.66 9.112±2.85 5.361±3.20 16.804±5.44 5.623±2.34 16.659±4.13 5.262±1.27 15.346±5.27 7.314±3.17 3.025±0.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006470 IDA protein dephosphorylation
GO:0007049 IEA cell cycle
GO:0016055 IEA Wnt signaling pathway
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IMP SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 ISS protein destabilization
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0042752 ISS regulation of circadian rhythm
GO:0042753 IMP positive regulation of circadian rhythm
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045862 ISS positive regulation of proteolysis
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265094 FBXW11-002 protein_coding Homo_sapiens 0 2218
ENST00000296933 FBXW11-001 protein_coding Homo_sapiens 0 2612
ENST00000393802 FBXW11-003 protein_coding Homo_sapiens 0 2215
ENST00000393804 FBXW11P1-001 processed_pseudogene Homo_sapiens 0 1672
ENST00000452808 RP4-713B5.2-001 processed_pseudogene Homo_sapiens 0 499
ENST00000517395 FBXW11-007 protein_coding Homo_sapiens 0 654
ENST00000518752 FBXW11-008 protein_coding Homo_sapiens 0 267
ENST00000519693 FBXW11-005 nonsense_mediated_decay Homo_sapiens 0 562
ENST00000520376 FBXW11-006 nonsense_mediated_decay Homo_sapiens 0 327
ENST00000522376 FBXW11-012 processed_transcript Homo_sapiens 0 691
ENST00000522507 FBXW11-011 processed_transcript Homo_sapiens 1.96182e-44 182
ENST00000522891 FBXW11-009 processed_transcript Homo_sapiens 0 913
ENST00000523843 FBXW11-004 nonsense_mediated_decay Homo_sapiens 0 2296

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