C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exportin 1, CRM1 homolog (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020290 Xpo1 10090 + 11:23256041-23298249 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020538 Xpo1-201 23256041-23297597 protein_coding
  ENSMUST00000102869 Xpo1-001 23256078-23298249 protein_coding
  ENSMUST00000102870 Xpo1-002 23256055-23296233 protein_coding
  ENSMUST00000109551 Xpo1-202 23256041-23297597 protein_coding
  ENSMUST00000136235 Xpo1-005 23256589-23267714 protein_coding
  ENSMUST00000149371 Xpo1-003 23256058-23282726 processed_transcript
  ENSMUST00000150750 Xpo1-004 23284644-23287451 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020538ENSMUST00000102869ENSMUST00000102870ENSMUST00000109551ENSMUST00000149371
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020538 2.280±0.69 N/A N/A 2.829±0.00 2.018±0.81 N/A 1.392±0.57 0.995±0.40 8.463±1.27 2.368±0.00 0.962±0.00 7.251±0.94 13.964±5.57 1.951±0.00
ENSMUST00000102869 1.506±0.00 0.990±0.00 2.230±0.00 7.861±0.00 0.782±0.00 N/A 0.342±0.00 0.478±0.00 2.155±1.33 N/A 0.459±0.00 2.025±0.38 5.655±0.00 0.959±0.00
ENSMUST00000102870 3.583±1.68 N/A 6.002±1.43 18.628±0.00 1.816±0.00 N/A 1.170±0.44 1.379±0.49 6.033±4.83 4.179±1.31 1.301±0.25 24.464±10.28 40.333±39.75 3.552±0.49
ENSMUST00000109551 N/A N/A 2.820±0.00 N/A N/A N/A N/A N/A 3.839±0.73 N/A N/A N/A 7.594±0.00 N/A
ENSMUST00000149371 N/A 6.270±1.31 N/A N/A 5.188±2.12 3.344±0.80 N/A 1.340±0.14 1.444±0.08 3.045±0.71 N/A 5.729±1.85 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000055 IEA ribosomal large subunit export from nucleus
GO:0000056 IEA ribosomal small subunit export from nucleus
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000776 ISS kinetochore
GO:0003723 IEA RNA binding
GO:0005487 IEA nucleocytoplasmic transporter activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005642 IEA annulate lamellae
GO:0005737 IEA cytoplasm
GO:0006611 IDA protein export from nucleus
GO:0008536 IEA Ran GTPase binding
GO:0008565 IDA protein transporter activity
GO:0010824 IMP regulation of centrosome duplication
GO:0016020 IEA membrane
GO:0019904 IEA protein domain specific binding
GO:0030529 ISO ribonucleoprotein complex
GO:0031965 IEA nuclear membrane
GO:0034504 IMP protein localization to nucleus
GO:0042176 IMP regulation of protein catabolic process
GO:0042493 IEA response to drug
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0046825 IMP regulation of protein export from nucleus
GO:0051028 IEA mRNA transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063229 xpo1b exportin 1 (CRM1 homolog, yeast) b protein_coding Danio_rerio
ENSDARG00000078041 xpo1a exportin 1 (CRM1 homolog, yeast) a protein_coding Danio_rerio
ENSG00000082898 XPO1 exportin 1 protein_coding Homo_sapiens

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