C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exportin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082898 XPO1 9606 - 2:61477849-61538626 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000401558 XPO1-001 61477849-61538283 protein_coding
  ENST00000404992 XPO1-006 61478338-61537110 protein_coding
  ENST00000406957 XPO1-004 61478700-61538248 protein_coding
  ENST00000420673 XPO1-019 61522611-61534278 protein_coding
  ENST00000422552 XPO1-018 61522626-61534512 protein_coding
  ENST00000428210 XPO1-005 61477934-61538231 nonsense_mediated_decay
  ENST00000436018 XPO1-009 61526471-61538626 protein_coding
  ENST00000437159 XPO1-024 61496994-61526518 nonsense_mediated_decay
  ENST00000443240 XPO1-008 61502006-61538626 protein_coding
  ENST00000449444 XPO1-016 61526462-61536588 protein_coding
  ENST00000451765 XPO1-015 61499765-61537117 protein_coding
  ENST00000457483 XPO1-017 61522630-61537640 protein_coding
  ENST00000460037 XPO1-027 61493638-61495573 retained_intron
  ENST00000461407 XPO1-007 61482625-61488663 retained_intron
  ENST00000468259 XPO1-022 61502290-61525775 processed_transcript
  ENST00000469337 XPO1-028 61492342-61492994 retained_intron
  ENST00000475744 XPO1-026 61496961-61498874 retained_intron
  ENST00000476585 XPO1-023 61502146-61526523 processed_transcript
  ENST00000481073 XPO1-014 61477935-61494743 retained_intron
  ENST00000481214 XPO1-020 61526067-61537694 processed_transcript
  ENST00000489954 XPO1-025 61499717-61502608 retained_intron
  ENST00000492182 XPO1-030 61482625-61485958 retained_intron
  ENST00000494468 XPO1-029 61485584-61488663 processed_transcript
  ENST00000495003 XPO1-021 61526151-61533968 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000401558ENST00000404992ENST00000406957ENST00000428210ENST00000481073
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000401558 9.380±0.00 8.927±0.00 1.037±0.00 7.984±4.15 5.434±2.51 3.896±0.50 4.000±1.33 6.336±0.00 3.403±0.04 3.291±0.54 3.512±1.74 15.460±6.76 8.441±2.33 9.585±0.23
ENST00000404992 N/A N/A 1.474±0.00 5.012±0.00 N/A 6.140±0.00 1.654±0.12 N/A 4.673±0.00 6.756±0.00 N/A 4.326±0.00 N/A N/A
ENST00000406957 N/A N/A N/A N/A 6.667±0.00 3.402±0.00 N/A N/A N/A N/A 1.464±0.00 9.984±0.00 N/A N/A
ENST00000428210 N/A N/A 0.916±0.00 1.177±0.00 1.652±0.00 N/A N/A 0.929±0.00 N/A 1.682±0.00 0.581±0.00 3.002±0.00 N/A N/A
ENST00000481073 N/A 5.674±0.00 1.803±0.00 N/A N/A N/A N/A N/A 4.260±0.00 4.292±0.00 N/A 20.241±9.82 13.668±0.00 23.052±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007N6 CIL_0007N6_0001 UCNEbase 2:61187520-61525646
CIL_0000ZI CIL_0000ZI_0002 CGP 2:61477849-61854143

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000055 IMP ribosomal large subunit export from nucleus
GO:0000056 IMP ribosomal small subunit export from nucleus
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0003723 IEA RNA binding
GO:0005215 TAS transporter activity
GO:0005487 IMP nucleocytoplasmic transporter activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 TAS nuclear envelope
GO:0005642 IDA annulate lamellae
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006611 IMP protein export from nucleus
GO:0006886 IEA intracellular protein transport
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008536 IEA Ran GTPase binding
GO:0008565 IEA protein transporter activity
GO:0010467 TAS gene expression
GO:0010824 IEA regulation of centrosome duplication
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019058 TAS viral life cycle
GO:0019904 IEA protein domain specific binding
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030529 IDA ribonucleoprotein complex
GO:0031965 IDA nuclear membrane
GO:0034504 IEA protein localization to nucleus
GO:0042176 IEA regulation of protein catabolic process
GO:0042493 IEA response to drug
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046825 IEA regulation of protein export from nucleus
GO:0051028 IEA mRNA transport
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063229 xpo1b exportin 1 (CRM1 homolog, yeast) b protein_coding Danio_rerio
ENSDARG00000078041 xpo1a exportin 1 (CRM1 homolog, yeast) a protein_coding Danio_rerio
ENSMUSG00000020290 Xpo1 exportin 1, CRM1 homolog (yeast) protein_coding Mus_musculus

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