C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC like kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020385 Clk4 10090 + 11:51261730-51281766 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000093132 Clk4-001 51263114-51281764 protein_coding
  ENSMUST00000109111 Clk4-004 51273451-51281764 protein_coding
  ENSMUST00000109113 Clk4-003 51263186-51281766 protein_coding
  ENSMUST00000126131 Clk4-006 51263150-51275259 nonsense_mediated_decay
  ENSMUST00000130641 Clk4-005 51261730-51273626 protein_coding
  ENSMUST00000133200 Clk4-010 51263162-51267504 retained_intron
  ENSMUST00000136587 Clk4-009 51263164-51272364 retained_intron
  ENSMUST00000140628 Clk4-012 51273612-51276237 retained_intron
  ENSMUST00000143468 Clk4-013 51280109-51281200 retained_intron
  ENSMUST00000146776 Clk4-008 51263174-51272060 retained_intron
  ENSMUST00000147007 Clk4-011 51274908-51275512 retained_intron
  ENSMUST00000148053 Clk4-007 51263169-51273622 nonsense_mediated_decay
  ENSMUST00000148467 Clk4-014 51271999-51277209 retained_intron
  ENSMUST00000153414 Clk4-002 51261730-51272019 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093132ENSMUST00000109111ENSMUST00000109113ENSMUST00000130641ENSMUST00000133200ENSMUST00000136587ENSMUST00000146776ENSMUST00000148467
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093132 4.864±0.00 2.750±0.70 10.694±0.64 9.838±1.13 4.737±0.45 2.085±0.48 3.500±0.76 4.226±0.79 7.888±4.32 6.039±1.11 7.999±1.39 6.199±3.82 9.886±2.88 18.154±0.00
ENSMUST00000109111 10.398±2.87 9.522±2.14 20.985±0.91 20.722±7.64 10.769±3.19 7.322±1.94 5.361±0.93 7.538±0.87 11.133±6.17 13.881±4.36 N/A 13.441±5.12 8.263±2.31 N/A
ENSMUST00000109113 N/A N/A N/A N/A N/A 3.610±0.00 2.560±0.11 3.142±0.00 7.714±0.00 N/A 3.228±0.00 3.717±0.00 5.089±0.72 N/A
ENSMUST00000130641 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 67.962±0.00
ENSMUST00000133200 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.661±0.57 N/A N/A
ENSMUST00000136587 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.835±0.00 N/A N/A
ENSMUST00000146776 N/A N/A N/A N/A N/A 5.416±0.00 N/A N/A N/A N/A N/A 9.221±0.95 N/A N/A
ENSMUST00000148467 N/A 2.209±0.90 4.204±0.00 3.836±0.00 1.807±0.00 N/A N/A N/A 5.605±2.27 N/A N/A 3.664±1.80 3.239±1.49 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IDA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0043484 IEA regulation of RNA splicing
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005908 clk4b CDC-like kinase 4b protein_coding Danio_rerio
ENSDARG00000089372 clk4a CDC-like kinase 4a protein_coding Danio_rerio
ENSG00000113240 CLK4 CDC-like kinase 4 protein_coding Homo_sapiens

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