C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC-like kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113240 CLK4 9606 - 5:178602664-178630615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316308 CLK4-001 178602664-178627114 protein_coding
  ENST00000519132 CLK4-008 178603270-178617388 retained_intron
  ENST00000519583 CLK4-013 178603272-178627041 retained_intron
  ENST00000520126 CLK4-007 178617731-178627052 retained_intron
  ENST00000520199 CLK4-006 178617071-178627054 retained_intron
  ENST00000520878 CLK4-005 178602664-178627088 retained_intron
  ENST00000520909 CLK4-002 178617697-178630615 retained_intron
  ENST00000520957 CLK4-012 178621812-178627030 protein_coding
  ENST00000521621 CLK4-003 178603270-178627029 nonsense_mediated_decay
  ENST00000522136 CLK4-009 178603168-178627055 nonsense_mediated_decay
  ENST00000522556 CLK4-004 178618694-178627112 nonsense_mediated_decay
  ENST00000522749 CLK4-011 178616882-178620119 processed_transcript
  ENST00000523013 CLK4-010 178621809-178623339 retained_intron
  ENST00000611575 CLK4-201 178603589-178627001 protein_coding
  ENST00000611733 CLK4-202 178602665-178627053 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316308ENST00000519583ENST00000520878ENST00000520957ENST00000521621ENST00000611575
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316308 1.092±0.00 4.068±0.00 N/A 2.226±0.00 3.048±0.00 4.021±0.00 1.326±0.00 4.147±0.00 1.875±0.60 3.328±0.00 2.412±0.00 3.506±1.27 1.028±0.55 4.085±0.00
ENST00000519583 0.381±0.00 N/A 3.249±0.00 3.149±0.00 1.557±0.72 3.297±0.00 0.781±0.17 1.585±0.12 0.825±0.55 3.738±0.00 N/A 1.130±0.44 0.121±0.00 N/A
ENST00000520878 N/A N/A 2.610±0.00 1.599±0.65 2.432±0.00 N/A 1.042±0.00 2.591±0.00 1.004±0.00 5.522±0.00 1.844±0.00 N/A 0.125±0.00 N/A
ENST00000520957 N/A N/A 4.334±0.00 N/A 2.750±0.00 5.048±0.00 1.754±0.00 2.916±0.00 2.189±0.00 6.082±0.00 1.300±0.00 1.988±0.00 N/A N/A
ENST00000521621 0.813±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.064±0.00 N/A N/A
ENST00000611575 N/A N/A N/A 5.170±0.00 3.777±0.00 3.329±0.00 2.004±0.00 N/A 2.097±1.15 3.126±0.00 3.856±1.60 2.834±0.54 0.881±0.34 9.718±5.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XD CIL_0000XD_0002 CGP 5:178237618-178630615

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043484 IMP regulation of RNA splicing
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005908 clk4b CDC-like kinase 4b protein_coding Danio_rerio
ENSDARG00000089372 clk4a CDC-like kinase 4a protein_coding Danio_rerio
ENSMUSG00000020385 Clk4 CDC like kinase 4 protein_coding Mus_musculus

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