C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020515 Cnot8 10090 + 11:58104153-58118594 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020822 Cnot8-001 58104153-58118594 protein_coding
  ENSMUST00000108843 Cnot8-003 58104229-58118594 protein_coding
  ENSMUST00000133923 Cnot8-004 58114027-58117258 processed_transcript
  ENSMUST00000134896 Cnot8-002 58104366-58111369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020822ENSMUST00000108843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020822 23.125±6.78 9.749±2.64 34.948±0.69 42.561±13.96 22.514±12.99 14.878±5.00 21.647±0.91 17.764±3.55 21.798±4.77 28.055±7.13 12.264±2.37 25.018±7.53 29.721±7.72 8.596±2.14
ENSMUST00000108843 4.071±0.11 5.092±2.24 N/A N/A 3.685±0.00 5.671±1.26 N/A 3.741±1.94 7.037±2.70 N/A 4.363±0.31 4.160±0.00 5.679±0.00 1.345±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099I CIL_00099I_0002 VISTA 11:57547462-58147793
CIL_00088D CIL_00088D_0002 VISTA 11:57627590-58231336
CIL_00023V CIL_00023V_0002 CGP 11:58104153-58168539

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004535 ISS poly(A)-specific ribonuclease activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 ISS positive regulation of cell proliferation
GO:0030014 ISS CCR4-NOT complex
GO:0031047 IEA gene silencing by RNA
GO:0043928 ISS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020043 cnot8 CCR4-NOT transcription complex, subunit 8 protein_coding Danio_rerio
ENSG00000155508 CNOT8 CCR4-NOT transcription complex, subunit 8 protein_coding Homo_sapiens

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