C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CCR4-NOT transcription complex, subunit 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020822 Cnot8-001 ENSMUSG00000020515 10090 + 11:58104153-58118594 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020822
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020822 23.125±6.78 9.749±2.64 34.948±0.69 42.561±13.96 22.514±12.99 14.878±5.00 21.647±0.91 17.764±3.55 21.798±4.77 28.055±7.13 12.264±2.37 25.018±7.53 29.721±7.72 8.596±2.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099I CIL_00099I_0002 VISTA 11:57547462-58147793
CIL_00088D CIL_00088D_0002 VISTA 11:57627590-58231336
CIL_00023V CIL_00023V_0002 CGP 11:58104153-58168539

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004535 ISS poly(A)-specific ribonuclease activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 ISS positive regulation of cell proliferation
GO:0030014 ISS CCR4-NOT complex
GO:0031047 IEA gene silencing by RNA
GO:0043928 ISS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000285896 CNOT8-001 protein_coding Homo_sapiens 0 1088
ENST00000403027 CNOT8-010 protein_coding Homo_sapiens 0 1088
ENST00000517876 CNOT8-006 protein_coding Homo_sapiens 0 1088
ENST00000518775 CNOT8-024 protein_coding Homo_sapiens 0 459
ENST00000519404 CNOT8-003 protein_coding Homo_sapiens 0 523
ENST00000519903 CNOT8-012 protein_coding Homo_sapiens 0 547
ENST00000520671 CNOT8-007 protein_coding Homo_sapiens 0 961
ENST00000521450 CNOT8-005 protein_coding Homo_sapiens 0 739
ENST00000521583 CNOT8-008 protein_coding Homo_sapiens 0 739
ENST00000521729 CNOT8-009 nonsense_mediated_decay Homo_sapiens 0 739
ENST00000522139 CNOT8-022 retained_intron Homo_sapiens 0 446
ENST00000522644 CNOT8-023 nonsense_mediated_decay Homo_sapiens 0 529
ENST00000523698 CNOT8-004 protein_coding Homo_sapiens 0 739
ENST00000524105 CNOT8-002 protein_coding Homo_sapiens 0 523

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