C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acid-sensing (proton-gated) ion channel 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020704 Asic2 10090 - 11:80880169-81968457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021045 Asic2-001 80880169-81153321 protein_coding
  ENSMUST00000066197 Asic2-002 80880169-81968457 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021045ENSMUST00000066197
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021045 4.183±3.36 0.556±0.24 0.465±0.01 5.392±1.62 0.106±0.05 0.498±0.09 N/A 0.406±0.17 0.008±0.00 0.023±0.01 0.058±0.02 6.934±2.73 0.149±0.12 0.094±0.02
ENSMUST00000066197 N/A 0.471±0.21 N/A 2.551±0.77 0.112±0.05 0.216±0.02 0.020±0.00 0.133±0.02 0.019±0.02 N/A 0.050±0.00 N/A 0.078±0.05 0.083±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074A CIL_00074A_0002 CGP 11:80858365-81968457

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003026 IMP regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
GO:0005216 IDA ion channel activity
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005261 IDA cation channel activity
GO:0005515 IPI protein binding
GO:0005887 IDA integral component of plasma membrane
GO:0006812 IDA cation transport
GO:0006814 IDA sodium ion transport
GO:0007602 IMP phototransduction
GO:0007605 IMP sensory perception of sound
GO:0009612 IMP response to mechanical stimulus
GO:0010447 IDA response to acidic pH
GO:0010468 IEA regulation of gene expression
GO:0015280 IDA ligand-gated sodium channel activity
GO:0016021 IDA integral component of membrane
GO:0019229 IMP regulation of vasoconstriction
GO:0022839 IDA ion gated channel activity
GO:0030193 IEA regulation of blood coagulation
GO:0034220 IDA ion transmembrane transport
GO:0034765 IMP regulation of ion transmembrane transport
GO:0035418 IMP protein localization to synapse
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IMP regulation of membrane potential
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043066 IMP negative regulation of apoptotic process
GO:0043197 IDA dendritic spine
GO:0045202 IDA synapse
GO:0050915 IEA sensory perception of sour taste
GO:0050974 IMP detection of mechanical stimulus involved in sensory perception
GO:0051965 IMP positive regulation of synapse assembly
GO:0071229 IEA cellular response to acid
GO:0071468 IEA cellular response to acidity
GO:0098655 IDA cation transmembrane transport
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006849 asic2 acid-sensing (proton-gated) ion channel 2 protein_coding Danio_rerio
ENSG00000108684 ASIC2 acid-sensing (proton-gated) ion channel 2 protein_coding Homo_sapiens

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