C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020733 Slc9a3r1 10090 + 11:115163341-115181181 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021077 Slc9a3r1-001 115163341-115181181 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021077
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021077 11.186±5.56 6.499±0.98 33.561±5.00 13.622±0.77 24.302±4.11 89.697±9.03 3.217±1.15 107.765±2.78 56.340±17.00 24.520±2.56 1.347±0.58 29.084±1.51 83.723±40.37 11.230±3.88

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IB CIL_0000IB_0002 CGP 11:115116214-115181181
CIL_00032B CIL_00032B_0002 CGP 11:115163341-115187859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003096 IMP renal sodium ion transport
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005813 IEA centrosome
GO:0005886 IEA plasma membrane
GO:0005902 ISS microvillus
GO:0007191 IMP adenylate cyclase-activating dopamine receptor signaling pathway
GO:0008013 IEA beta-catenin binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0010642 IMP negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010766 IMP negative regulation of sodium ion transport
GO:0014067 IGI negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016324 IDA apical plasma membrane
GO:0017081 ISS chloride channel regulator activity
GO:0019902 IPI phosphatase binding
GO:0019904 IEA protein domain specific binding
GO:0019933 ISA cAMP-mediated signaling
GO:0030033 IEA microvillus assembly
GO:0030036 IMP actin cytoskeleton organization
GO:0030165 IEA PDZ domain binding
GO:0030336 IGI negative regulation of cell migration
GO:0030643 IMP cellular phosphate ion homeostasis
GO:0031526 IDA brush border membrane
GO:0031528 ISS microvillus membrane
GO:0031698 IEA beta-2 adrenergic receptor binding
GO:0031982 IEA vesicle
GO:0032403 IEA protein complex binding
GO:0032416 IMP negative regulation of sodium:proton antiporter activity
GO:0032782 IMP bile acid secretion
GO:0032947 IEA protein complex scaffold
GO:0034613 IMP cellular protein localization
GO:0034635 IMP glutathione transport
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043621 IEA protein self-association
GO:0044062 IMP regulation of excretion
GO:0045121 IEA membrane raft
GO:0045177 IDA apical part of cell
GO:0045859 IMP regulation of protein kinase activity
GO:0050780 IDA dopamine receptor binding
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060158 IMP phospholipase C-activating dopamine receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0070293 IMP renal absorption
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0070851 IEA growth factor receptor binding
GO:0071944 IEA cell periphery
GO:0097225 IDA sperm midpiece
GO:0097291 ISS renal phosphate ion absorption
GO:2000146 ISS negative regulation of cell motility
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000068 slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 protein_coding Danio_rerio
ENSDARG00000074042 SLC9A3R1 (2 of 2) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 protein_coding Danio_rerio
ENSG00000109062 SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 protein_coding Homo_sapiens

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