C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nitric oxide synthase 2, inducible
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020826 Nos2 10090 + 11:78920787-78960254 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018610 Nos2-001 78920787-78960254 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018610
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018610 2.384±1.26 1.394±0.50 0.507±0.00 0.201±0.17 1.376±0.42 0.487±0.09 1.801±0.34 0.413±0.17 0.026±0.01 1.265±0.24 0.749±0.23 5.553±2.67 5.444±4.07 0.150±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SM CIL_0007SM_0002 VISTA 11:78750979-79355443
CIL_0003LO CIL_0003LO_0002 CGP 11:78826584-78960254

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IDA nitric-oxide synthase activity
GO:0005102 IEA receptor binding
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005516 TAS calmodulin binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005777 IEA peroxisome
GO:0005829 TAS cytosol
GO:0006527 IDA arginine catabolic process
GO:0006801 IMP superoxide metabolic process
GO:0006809 IDA nitric oxide biosynthetic process
GO:0006954 TAS inflammatory response
GO:0007263 IBA nitric oxide mediated signal transduction
GO:0007623 IEP circadian rhythm
GO:0010181 IDA FMN binding
GO:0010629 IGI negative regulation of gene expression
GO:0018119 IDA peptidyl-cysteine S-nitrosylation
GO:0020037 IDA heme binding
GO:0030863 IDA cortical cytoskeleton
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0032496 IDA response to lipopolysaccharide
GO:0034617 IDA tetrahydrobiopterin binding
GO:0034618 IDA arginine binding
GO:0042127 IGI regulation of cell proliferation
GO:0042177 IDA negative regulation of protein catabolic process
GO:0042742 IMP defense response to bacterium
GO:0042803 IDA protein homodimerization activity
GO:0045776 IBA negative regulation of blood pressure
GO:0045909 IBA positive regulation of vasodilation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050660 IDA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0050796 IEA regulation of insulin secretion
GO:0051712 IEA positive regulation of killing of cells of other organism
GO:0055114 IEA oxidation-reduction process
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071346 IDA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026925 nos2a nitric oxide synthase 2a, inducible protein_coding Danio_rerio
ENSDARG00000031976 nos2b nitric oxide synthase 2b, inducible protein_coding Danio_rerio
ENSG00000007171 NOS2 nitric oxide synthase 2, inducible protein_coding Homo_sapiens

Loading