C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal transducer and activator of transcription 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020919 Stat5b 10090 - 11:100780731-100850724 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004143 Stat5b-001 100780731-100850724 protein_coding
  ENSMUST00000107358 Stat5b-002 100780731-100822528 protein_coding
  ENSMUST00000126266 Stat5b-003 100798667-100850538 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004143ENSMUST00000107358
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004143 13.828±3.31 18.110±5.88 6.721±0.04 4.955±1.24 19.353±6.82 7.489±1.98 11.821±3.73 7.563±3.02 10.480±1.65 19.132±1.57 11.856±5.66 23.767±5.17 4.466±3.48 0.975±0.25
ENSMUST00000107358 N/A 10.292±4.39 N/A N/A 4.711±0.81 1.676±0.00 2.461±0.38 N/A 5.569±0.67 N/A 27.042±8.03 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000KW CIL_0000KW_0003 CGP 11:100766032-100850724
CIL_0006I7 CIL_0006I7_0002 CGP 11:100780731-100885169

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000255 IMP allantoin metabolic process
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001553 IGI luteinization
GO:0001666 IEA response to hypoxia
GO:0001779 IGI natural killer cell differentiation
GO:0001889 IEA liver development
GO:0003677 IDA DNA binding
GO:0003682 ISS chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0004871 IGI signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006101 IMP citrate metabolic process
GO:0006103 IMP 2-oxoglutarate metabolic process
GO:0006105 IMP succinate metabolic process
GO:0006107 IMP oxaloacetate metabolic process
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006549 IMP isoleucine metabolic process
GO:0006573 IMP valine metabolic process
GO:0006600 IMP creatine metabolic process
GO:0006631 IMP fatty acid metabolic process
GO:0006953 IEA acute-phase response
GO:0007259 IDA JAK-STAT cascade
GO:0007548 IMP sex differentiation
GO:0007565 IGI female pregnancy
GO:0007595 IMP lactation
GO:0008284 IGI positive regulation of cell proliferation
GO:0019218 IGI regulation of steroid metabolic process
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019530 IMP taurine metabolic process
GO:0019903 IPI protein phosphatase binding
GO:0019915 IGI lipid storage
GO:0030155 IMP regulation of cell adhesion
GO:0030856 IMP regulation of epithelial cell differentiation
GO:0032355 IEA response to estradiol
GO:0032496 IEA response to lipopolysaccharide
GO:0032819 IMP positive regulation of natural killer cell proliferation
GO:0032825 IMP positive regulation of natural killer cell differentiation
GO:0032870 IEA cellular response to hormone stimulus
GO:0033077 IGI T cell differentiation in thymus
GO:0035259 IEA glucocorticoid receptor binding
GO:0038161 IDA prolactin signaling pathway
GO:0040014 IDA regulation of multicellular organism growth
GO:0040018 IGI positive regulation of multicellular organism growth
GO:0042104 IGI positive regulation of activated T cell proliferation
GO:0042448 IGI progesterone metabolic process
GO:0043029 IGI T cell homeostasis
GO:0043066 IGI negative regulation of apoptotic process
GO:0043434 IEA response to peptide hormone
GO:0043565 IEA sequence-specific DNA binding
GO:0045086 IGI positive regulation of interleukin-2 biosynthetic process
GO:0045471 IEA response to ethanol
GO:0045579 IGI positive regulation of B cell differentiation
GO:0045588 IGI positive regulation of gamma-delta T cell differentiation
GO:0045621 IGI positive regulation of lymphocyte differentiation
GO:0045647 IGI negative regulation of erythrocyte differentiation
GO:0045931 IGI positive regulation of mitotic cell cycle
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0045954 IMP positive regulation of natural killer cell mediated cytotoxicity
GO:0046449 IMP creatinine metabolic process
GO:0046543 IMP development of secondary female sexual characteristics
GO:0046544 IGI development of secondary male sexual characteristics
GO:0046983 IDA protein dimerization activity
GO:0048541 IGI Peyer's patch development
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050729 IGI positive regulation of inflammatory response
GO:0051272 IEA positive regulation of cellular component movement
GO:0060397 IDA JAK-STAT cascade involved in growth hormone signaling pathway
GO:0070669 IMP response to interleukin-2
GO:0070670 IMP response to interleukin-4
GO:0070672 IMP response to interleukin-15
GO:0071363 IDA cellular response to growth factor stimulus
GO:0071364 ISS cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019392 stat5.1 signal transducer and activator of transcription 5.1 protein_coding Danio_rerio
ENSDARG00000055588 stat5.2 signal transducer and activator of transcription 5.2 protein_coding Danio_rerio
ENSG00000173757 STAT5B signal transducer and activator of transcription 5B protein_coding Homo_sapiens

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