C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2, subunit 1 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021116 Eif2s1 10090 + 12:78861819-78887010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071230 Eif2s1-001 78861819-78887010 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071230
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071230 13.510±3.78 6.297±2.05 7.321±0.22 5.892±1.80 8.365±2.93 6.167±1.85 5.613±1.31 7.164±1.76 11.166±6.77 7.160±2.42 4.969±2.42 9.468±4.82 27.177±12.12 19.777±9.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001KG CIL_0001KG_0003 CGP 12:78842989-78887010
CIL_00010S CIL_00010S_0002 CGP 12:78861819-78906964

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 ISS translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005850 IEA eukaryotic translation initiation factor 2 complex
GO:0005851 ISS eukaryotic translation initiation factor 2B complex
GO:0006412 IDA translation
GO:0006413 IEA translational initiation
GO:0010494 IDA cytoplasmic stress granule
GO:0016020 IEA membrane
GO:0043022 ISS ribosome binding
GO:0043558 IDA regulation of translational initiation in response to stress
GO:0044822 IEA poly(A) RNA binding
GO:0046777 IDA protein autophosphorylation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005827 eif2s1a eukaryotic translation initiation factor 2, subunit 1 alpha a protein_coding Danio_rerio
ENSDARG00000052178 eif2s1b eukaryotic translation initiation factor 2, subunit 1 alpha b protein_coding Danio_rerio
ENSG00000134001 EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa protein_coding Homo_sapiens

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