C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 46, subfamily a, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021259 Cyp46a1 10090 + 12:108334377-108362231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021684 Cyp46a1-201 108334377-108362231 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021684
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021684 0.652±0.18 2.825±0.82 1.096±0.15 29.818±32.84 0.781±0.35 0.410±0.09 0.313±0.10 0.761±0.43 0.435±0.34 0.295±0.08 0.126±0.04 1.175±0.63 0.841±0.32 4.082±1.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CK CIL_0009CK_0002 VISTA 12:107949271-108552884
CIL_0003HF CIL_0003HF_0002 CGP 12:108306270-108362231
CIL_0003HG CIL_0003HG_0002 CGP 12:108334377-108539617

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IEA endoplasmic reticulum
GO:0006707 ISS cholesterol catabolic process
GO:0006805 ISS xenobiotic metabolic process
GO:0016021 IEA integral component of membrane
GO:0020037 ISS heme binding
GO:0033781 ISS cholesterol 24-hydroxylase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004262 cyp46a2 cytochrome P450, family 46, subfamily A, polypeptide 2 protein_coding Danio_rerio
ENSDARG00000012137 cyp46a1 cytochrome P450, family 46, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000039492 cyp46a4 cytochrome P450, family 46, subfamily A, polypeptide 4 protein_coding Danio_rerio
ENSDARG00000089177 CYP46A1 (4 of 5) cytochrome P450, family 46, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000093477 CYP46A1 (5 of 5) cytochrome P450, family 46, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSG00000036530 CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 protein_coding Homo_sapiens

Loading