C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome P450, family 46, subfamily a, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021684 Cyp46a1-201 ENSMUSG00000021259 10090 + 12:108334377-108362231 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021684
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021684 0.652±0.18 2.825±0.82 1.096±0.15 29.818±32.84 0.781±0.35 0.410±0.09 0.313±0.10 0.761±0.43 0.435±0.34 0.295±0.08 0.126±0.04 1.175±0.63 0.841±0.32 4.082±1.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CK CIL_0009CK_0002 VISTA 12:107949271-108552884
CIL_0003HF CIL_0003HF_0002 CGP 12:108306270-108362231
CIL_0003HG CIL_0003HG_0002 CGP 12:108334377-108539617

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IEA endoplasmic reticulum
GO:0006707 ISS cholesterol catabolic process
GO:0006805 ISS xenobiotic metabolic process
GO:0016021 IEA integral component of membrane
GO:0020037 ISS heme binding
GO:0033781 ISS cholesterol 24-hydroxylase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261835 CYP46A1-001 protein_coding Homo_sapiens 0 2039
ENST00000380228 CYP46A1-003 protein_coding Homo_sapiens 0 1711
ENST00000554176 CYP46A1-004 protein_coding Homo_sapiens 0 876
ENST00000554611 CYP46A1-002 nonsense_mediated_decay Homo_sapiens 0 503
ENST00000554917 CYP46A1-005 nonsense_mediated_decay Homo_sapiens 0 575
ENST00000556313 CYP46A1-006 protein_coding Homo_sapiens 0 549
ENST00000556822 CYP46A1-007 retained_intron Homo_sapiens 0 279

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