C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thiopurine methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021376 Tpmt 10090 - 13:47025170-47044737 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021806 Tpmt-001 47025170-47043210 protein_coding
  ENSMUST00000110118 Tpmt-002 47025179-47043124 protein_coding
  ENSMUST00000124948 Tpmt-007 47040114-47043138 protein_coding
  ENSMUST00000133100 Tpmt-003 47039698-47043144 retained_intron
  ENSMUST00000136864 Tpmt-006 47028882-47043343 protein_coding
  ENSMUST00000151509 Tpmt-005 47025368-47044664 nonsense_mediated_decay
  ENSMUST00000154802 Tpmt-004 47028901-47044737 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021806ENSMUST00000110118ENSMUST00000124948ENSMUST00000136864ENSMUST00000151509ENSMUST00000154802
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021806 2.321±0.00 1.097±0.26 2.570±0.43 2.902±1.89 0.905±0.00 2.633±1.65 1.000±0.51 13.845±0.00 5.688±1.57 0.839±0.28 0.454±0.13 1.134±1.11 3.192±3.00 1.427±0.00
ENSMUST00000110118 N/A 0.385±0.00 N/A 0.674±0.00 1.344±0.00 0.672±0.00 0.312±0.00 N/A 5.877±3.31 N/A N/A 1.916±1.21 0.775±0.36 0.136±0.00
ENSMUST00000124948 N/A N/A N/A 1.046±0.00 N/A 3.238±0.00 N/A N/A 3.288±0.00 0.896±0.00 N/A 4.117±0.00 3.428±2.51 N/A
ENSMUST00000136864 N/A 0.204±0.07 N/A 1.224±0.00 N/A N/A 0.471±0.15 N/A 1.297±0.00 0.158±0.00 0.686±0.00 0.819±0.06 1.488±0.00 N/A
ENSMUST00000151509 N/A 0.133±0.00 N/A N/A N/A N/A N/A N/A N/A 0.090±0.00 N/A 0.383±0.04 N/A N/A
ENSMUST00000154802 N/A 0.151±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.498±0.16 N/A 0.663±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081D CIL_00081D_0002 VISTA 13:46435395-47036634
CIL_00090E CIL_00090E_0002 VISTA 13:46584783-47186478
CIL_0008X6 CIL_0008X6_0002 VISTA 13:47010584-47612217
CIL_0003RL CIL_0003RL_0002 CGP 13:47012558-47044737
CIL_0003RU CIL_0003RU_0002 CGP 13:47025170-47084613

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0008119 IDA thiopurine S-methyltransferase activity
GO:0032259 IEA methylation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028012 TPMT (1 of 2) thiopurine S-methyltransferase protein_coding Danio_rerio
ENSDARG00000055974 TPMT (2 of 2) thiopurine S-methyltransferase protein_coding Danio_rerio
ENSG00000137364 TPMT thiopurine S-methyltransferase protein_coding Homo_sapiens

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