C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paired-like homeodomain transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021506 Pitx1 10090 - 13:55825051-55836192 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021968 Pitx1-001 55825051-55831425 protein_coding
  ENSMUST00000173618 Pitx1-002 55828474-55836192 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021968ENSMUST00000173618
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021968 0.424±0.38 0.052±0.02 37.583±1.66 0.219±0.17 0.234±0.14 9.336±0.69 0.044±0.01 0.038±0.02 0.063±0.08 3.054±3.13 0.108±0.07 0.388±0.16 4.537±3.16 0.067±0.02
ENSMUST00000173618 N/A 0.073±0.03 N/A N/A N/A N/A N/A N/A 0.182±0.00 N/A 0.137±0.06 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AP CIL_0009AP_0002 VISTA 13:55516415-56118354
CIL_0007JT CIL_0007JT_0005 UCNEbase 13:55750083-56024842
CIL_0005XU CIL_0005XU_0002 CGP 13:55784568-55836192

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001190 IPI RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001501 IMP skeletal system development
GO:0003677 IEA DNA binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0014707 IMP branchiomeric skeletal muscle development
GO:0021983 IMP pituitary gland development
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0035137 IMP hindlimb morphogenesis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048625 IMP myoblast fate commitment
GO:0051216 IMP cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042785 pitx1 paired-like homeodomain transcription factor 1 protein_coding Danio_rerio
ENSG00000069011 PITX1 paired-like homeodomain 1 protein_coding Homo_sapiens

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