C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-ray repair complementing defective repair in Chinese hamster cells 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021615 Xrcc4 10090 - 13:89774027-90089608 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022115 Xrcc4-001 89848921-90089608 protein_coding
  ENSMUST00000159199 Xrcc4-002 89774027-90089523 nonsense_mediated_decay
  ENSMUST00000160232 Xrcc4-003 90062040-90089536 protein_coding
  ENSMUST00000161396 Xrcc4-004 90062075-90089082 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022115
Transcript ID Adrenal Bladder Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022115 0.990±0.00 5.888±0.29 1.703±0.24 2.170±0.34 3.749±0.00 2.538±0.35 3.328±0.31 4.230±2.47 4.535±0.00 6.287±3.40

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0002328 IMP pro-B cell differentiation
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005813 IEA centrosome
GO:0005829 IEA cytosol
GO:0005958 IDA DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006266 IDA DNA ligation
GO:0006302 IMP double-strand break repair
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0007417 IMP central nervous system development
GO:0008022 IEA protein C-terminus binding
GO:0010165 IMP response to X-ray
GO:0010212 IMP response to ionizing radiation
GO:0010332 IMP response to gamma radiation
GO:0030054 IEA cell junction
GO:0032807 IEA DNA ligase IV complex
GO:0033077 IMP T cell differentiation in thymus
GO:0033151 IMP V(D)J recombination
GO:0033152 IMP immunoglobulin V(D)J recombination
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045190 IMP isotype switching
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0050769 IMP positive regulation of neurogenesis
GO:0051103 IEA DNA ligation involved in DNA repair
GO:0051351 IEA positive regulation of ligase activity
GO:0070419 ISS nonhomologous end joining complex
GO:0071285 IEA cellular response to lithium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010732 xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 protein_coding Danio_rerio
ENSG00000152422 XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 protein_coding Homo_sapiens

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