C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: occludin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021638 Ocln 10090 - 13:100496507-100552718 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022140 Ocln-003 100497763-100552718 protein_coding
  ENSMUST00000069756 Ocln-001 100496507-100552498 protein_coding
  ENSMUST00000159459 Ocln-004 100497767-100552623 protein_coding
  ENSMUST00000159515 Ocln-005 100511594-100552460 protein_coding
  ENSMUST00000160859 Ocln-002 100498114-100552481 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022140ENSMUST00000069756ENSMUST00000159459ENSMUST00000159515ENSMUST00000160859
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022140 3.974±0.39 0.695±0.18 1.551±0.64 0.750±0.13 1.163±0.27 17.384±2.17 N/A 4.992±0.69 3.153±1.27 11.022±2.05 N/A 1.216±0.47 6.422±0.00 0.744±0.11
ENSMUST00000069756 1.052±0.25 0.150±0.00 1.161±0.10 0.389±0.03 0.293±0.13 6.486±1.63 0.074±0.04 1.847±0.25 1.346±0.42 3.980±0.70 0.021±0.00 0.515±0.29 1.833±1.28 0.412±0.09
ENSMUST00000159459 0.041±0.00 N/A 1.018±0.07 N/A N/A N/A N/A N/A 0.568±0.00 N/A 0.034±0.02 0.755±0.13 0.855±0.14 0.749±0.39
ENSMUST00000159515 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.132±0.04 N/A N/A N/A
ENSMUST00000160859 0.401±0.34 0.251±0.00 1.406±0.16 1.266±0.00 1.233±0.79 4.536±1.02 0.131±0.03 1.715±0.23 0.953±0.15 3.934±1.27 0.039±0.00 1.502±0.82 1.101±0.61 0.643±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SX CIL_0001SX_0002 CGP 13:100496507-100616971

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 IDA tight junction
GO:0008119 IEA thiopurine S-methyltransferase activity
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0009986 ISO cell surface
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0016327 IDA apicolateral plasma membrane
GO:0019904 IEA protein domain specific binding
GO:0030054 IEA cell junction
GO:0030139 IDA endocytic vesicle
GO:0031410 IEA cytoplasmic vesicle
GO:0032259 IEA methylation
GO:0045216 IEA cell-cell junction organization
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046500 IEA S-adenosylmethionine metabolic process
GO:0070830 IEA tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003091 oclnb occludin b protein_coding Danio_rerio
ENSDARG00000005108 oclna occludin a protein_coding Danio_rerio
ENSG00000197822 OCLN occludin protein_coding Homo_sapiens

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