C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: occludin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197822 OCLN 9606 + 5:69492292-69558104 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355237 OCLN-001 69492292-69558104 protein_coding
  ENST00000396442 OCLN-002 69492790-69553671 protein_coding
  ENST00000510666 OCLN-004 69544744-69553711 retained_intron
  ENST00000514370 OCLN-003 69544692-69553999 processed_transcript
  ENST00000538151 OCLN-201 69504177-69558104 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355237ENST00000396442ENST00000514370ENST00000538151
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355237 0.178±0.00 0.094±0.00 0.267±0.08 0.473±0.25 N/A 1.783±0.33 0.622±0.00 3.749±2.06 N/A 1.634±0.85 0.587±0.30 0.288±0.00
ENST00000396442 N/A 0.299±0.00 1.370±0.00 1.554±0.00 N/A 3.444±0.00 1.512±0.00 N/A N/A 2.750±0.00 N/A N/A
ENST00000514370 N/A N/A N/A N/A 0.147±0.00 N/A N/A N/A N/A 2.496±0.00 N/A N/A
ENST00000538151 0.182±0.00 0.312±0.00 0.427±0.00 N/A N/A 0.656±0.00 N/A N/A 0.052±0.00 0.796±0.33 0.527±0.00 0.774±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000774 CIL_000774_0002 CGP 5:69415112-69558104
CIL_0005K7 CIL_0005K7_0002 CGP 5:69492292-69594723

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 IDA:IEA tight junction
GO:0006461 TAS protein complex assembly
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008119 IEA thiopurine S-methyltransferase activity
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016327 IEA apicolateral plasma membrane
GO:0019904 IPI protein domain specific binding
GO:0030054 IDA cell junction
GO:0030139 IEA endocytic vesicle
GO:0031410 IDA cytoplasmic vesicle
GO:0032259 IEA methylation
GO:0045216 IMP cell-cell junction organization
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046500 IEA S-adenosylmethionine metabolic process
GO:0070830 IMP tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003091 oclnb occludin b protein_coding Danio_rerio
ENSDARG00000005108 oclna occludin a protein_coding Danio_rerio
ENSMUSG00000021638 Ocln occludin protein_coding Mus_musculus

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