C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thyroid hormone receptor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021779 Thrb 10090 + 14:17660960-18038088 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022303 Thrb-002 17660960-18036559 protein_coding
  ENSMUST00000022304 Thrb-001 17981644-18038086 protein_coding
  ENSMUST00000091471 Thrb-201 17660960-18038088 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022303ENSMUST00000091471
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022303 N/A N/A N/A 0.839±0.00 N/A N/A 0.522±0.00 N/A N/A N/A N/A 0.609±0.39 0.178±0.07 0.062±0.00
ENSMUST00000091471 2.200±0.98 5.268±2.99 3.920±0.00 0.716±0.94 0.596±0.23 0.764±0.33 0.381±0.00 4.205±0.00 1.566±1.19 1.864±0.00 1.186±0.53 1.538±0.96 1.379±0.14 0.110±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004887 ISS thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0007605 IMP sensory perception of sound
GO:0007621 IMP negative regulation of female receptivity
GO:0008016 IMP regulation of heart contraction
GO:0008050 IMP female courtship behavior
GO:0008270 IEA zinc ion binding
GO:0009887 IMP organ morphogenesis
GO:0019899 IEA enzyme binding
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031490 IDA chromatin DNA binding
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0060509 IGI Type I pneumocyte differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0070324 ISS thyroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021163 thrb thyroid hormone receptor beta protein_coding Danio_rerio
ENSG00000151090 THRB thyroid hormone receptor, beta protein_coding Homo_sapiens

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