C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thyroid hormone receptor, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151090 THRB 9606 - 3:24117160-24495282 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280696 THRB-003 24122838-24165595 protein_coding
  ENST00000356447 THRB-001 24118210-24494822 protein_coding
  ENST00000396671 THRB-201 24117160-24494822 protein_coding
  ENST00000413780 THRB-011 24146718-24495005 protein_coding
  ENST00000415021 THRB-005 24152408-24494731 protein_coding
  ENST00000416420 THRB-004 24122208-24494811 protein_coding
  ENST00000418247 THRB-012 24190168-24494803 protein_coding
  ENST00000428492 THRB-009 24190154-24494771 protein_coding
  ENST00000431815 THRB-008 24152431-24494797 protein_coding
  ENST00000447414 THRB-010 24152463-24495282 protein_coding
  ENST00000447875 THRB-006 24152408-24494751 protein_coding
  ENST00000453729 THRB-002 24152410-24494962 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000280696ENST00000356447ENST00000396671ENST00000415021
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000280696 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.275±0.00
ENST00000356447 4.082±0.00 1.485±0.00 2.179±0.00 6.359±0.00 4.059±2.27 1.895±0.14 2.018±0.90 3.138±0.28 2.869±0.28 1.418±0.57 1.962±1.25 0.809±0.22 1.479±0.23 1.348±0.00
ENST00000396671 N/A N/A N/A 1.344±0.00 0.353±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.066±0.00
ENST00000415021 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.068±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025B CIL_00025B_0002 CGP 3:23945260-24495282

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0003677 TAS DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003714 TAS transcription corepressor activity
GO:0004887 IDA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 TAS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007605 IEA sensory perception of sound
GO:0007621 IEA negative regulation of female receptivity
GO:0008016 IEA regulation of heart contraction
GO:0008050 IEA female courtship behavior
GO:0008270 IEA zinc ion binding
GO:0009887 IEA organ morphogenesis
GO:0010467 TAS gene expression
GO:0019899 IPI enzyme binding
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031490 IEA chromatin DNA binding
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060509 IEA Type I pneumocyte differentiation
GO:0070062 IDA extracellular vesicular exosome
GO:0070324 IDA thyroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021163 thrb thyroid hormone receptor beta protein_coding Danio_rerio
ENSMUSG00000021779 Thrb thyroid hormone receptor beta protein_coding Mus_musculus

Loading