C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 2-hydroxyacyl-CoA lyase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021884 Hacl1 10090 - 14:31552905-31641286 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022437 Hacl1-001 31607226-31640964 protein_coding
  ENSMUST00000127204 Hacl1-005 31608011-31640912 protein_coding
  ENSMUST00000128629 Hacl1-006 31629767-31641257 nonsense_mediated_decay
  ENSMUST00000134626 Hacl1-004 31626426-31641172 nonsense_mediated_decay
  ENSMUST00000135751 Hacl1-009 31635648-31641286 retained_intron
  ENSMUST00000139501 Hacl1-010 31607969-31610334 processed_transcript
  ENSMUST00000140078 Hacl1-003 31607665-31614317 processed_transcript
  ENSMUST00000155210 Hacl1-007 31630579-31640946 retained_intron
  ENSMUST00000156189 Hacl1-008 31635509-31640911 retained_intron
  ENSMUST00000156431 Hacl1-002 31598730-31640944 nonsense_mediated_decay
  ENSMUST00000165955 Hacl1-012 31608011-31640878 nonsense_mediated_decay
  ENSMUST00000167066 Hacl1-011 31608011-31640878 protein_coding
  ENSMUST00000167175 Hacl1-014 31552905-31640878 nonsense_mediated_decay
  ENSMUST00000171414 Hacl1-013 31608011-31640878 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000022437ENSMUST00000127204ENSMUST00000165955ENSMUST00000167066
Transcript ID Adipose Bladder Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000022437 6.096±0.00 3.431±0.01 N/A N/A 15.962±2.89 51.849±37.75 1.161±0.19 N/A N/A 2.409±0.08
ENSMUST00000127204 13.957±4.81 4.374±0.51 N/A 11.116±0.00 34.664±12.08 38.075±22.42 2.085±0.30 9.072±0.00 2.566±0.00 4.405±2.02
ENSMUST00000165955 N/A N/A 1.739±0.00 N/A N/A N/A 2.786±0.00 N/A 2.663±0.57 N/A
ENSMUST00000167066 N/A N/A N/A N/A 34.064±12.27 169.398±10.62 N/A 5.148±0.00 N/A 1.739±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005AJ CIL_0005AJ_0002 CGP 14:31495079-31591343
CIL_0005AM CIL_0005AM_0002 CGP 14:31523082-31641286
CIL_0005AL CIL_0005AL_0002 CGP 14:31552905-31668579

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001561 ISS fatty acid alpha-oxidation
GO:0005102 IEA receptor binding
GO:0005777 TAS:ISS peroxisome
GO:0006629 IDA lipid metabolic process
GO:0016829 IDA lyase activity
GO:0016830 ISS carbon-carbon lyase activity
GO:0030976 ISS thiamine pyrophosphate binding
GO:0042802 IEA identical protein binding
GO:0048037 IEA cofactor binding
GO:0051259 IEA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020529 hacl1 2-hydroxyacyl-CoA lyase 1 protein_coding Danio_rerio
ENSG00000131373 HACL1 2-hydroxyacyl-CoA lyase 1 protein_coding Homo_sapiens

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