C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 2-hydroxyacyl-CoA lyase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131373 HACL1 9606 - 3:15560704-15601831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321169 HACL1-001 15560704-15601831 protein_coding
  ENST00000383779 HACL1-006 15560746-15601557 nonsense_mediated_decay
  ENST00000414979 HACL1-009 15582878-15601561 protein_coding
  ENST00000421993 HACL1-008 15579900-15601592 protein_coding
  ENST00000422591 HACL1-004 15563358-15601569 nonsense_mediated_decay
  ENST00000435217 HACL1-003 15560716-15601569 protein_coding
  ENST00000451445 HACL1-002 15560746-15601587 protein_coding
  ENST00000456194 HACL1-005 15560747-15601569 protein_coding
  ENST00000457447 HACL1-007 15560807-15601569 protein_coding
  ENST00000460907 HACL1-010 15596152-15601569 retained_intron
  ENST00000469454 HACL1-012 15595915-15601185 retained_intron
  ENST00000472857 HACL1-011 15600801-15601546 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321169ENST00000383779ENST00000422591ENST00000435217ENST00000451445ENST00000456194
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321169 N/A N/A N/A N/A 1.498±0.00 0.337±0.00 N/A 0.598±0.00 N/A N/A 3.611±0.00 N/A N/A
ENST00000383779 N/A 3.458±0.00 2.419±0.00 N/A N/A N/A N/A 4.692±0.00 N/A N/A N/A N/A N/A
ENST00000422591 N/A 6.108±0.00 4.627±0.00 10.449±0.00 2.384±0.00 N/A 4.224±0.00 N/A 1.611±0.00 3.602±0.00 2.605±0.00 4.308±0.00 9.142±3.47
ENST00000435217 N/A N/A 3.384±0.00 N/A N/A N/A N/A N/A 3.530±0.00 N/A 2.896±0.00 N/A 15.953±0.00
ENST00000451445 3.991±0.00 N/A N/A 1.698±0.00 1.273±0.00 1.891±0.00 2.469±0.00 3.958±2.14 2.406±0.00 3.609±2.35 N/A 5.016±0.00 N/A
ENST00000456194 4.038±0.00 3.718±0.00 N/A N/A N/A 1.872±0.00 9.362±0.00 4.732±0.00 N/A N/A 1.278±0.37 3.748±0.13 5.830±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005AM CIL_0005AM_0001 CGP 3:15450133-15601831
CIL_0005AL CIL_0005AL_0001 CGP 3:15560704-15645822

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001561 IDA fatty acid alpha-oxidation
GO:0003824 IEA catalytic activity
GO:0005102 IPI receptor binding
GO:0005777 IDA peroxisome
GO:0005782 TAS peroxisomal matrix
GO:0006629 IEA lipid metabolic process
GO:0008152 IEA metabolic process
GO:0016829 IEA lyase activity
GO:0016830 IDA carbon-carbon lyase activity
GO:0019385 IEA methanogenesis, from acetate
GO:0030976 IDA:IEA thiamine pyrophosphate binding
GO:0042802 IPI identical protein binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0048037 IDA cofactor binding
GO:0051259 IDA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020529 hacl1 2-hydroxyacyl-CoA lyase 1 protein_coding Danio_rerio
ENSMUSG00000021884 Hacl1 2-hydroxyacyl-CoA lyase 1 protein_coding Mus_musculus

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