C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021939 Ctsb 10090 + 14:63122462-63145919 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006235 Ctsb-201 63122462-63145919 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006235
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006235 362.293±106.58 732.548±122.54 68.571±13.54 28.760±10.63 393.392±96.14 162.551±16.43 115.186±14.01 200.475±32.56 168.957±63.80 131.698±14.01 11.337±1.80 252.216±82.31 131.364±84.12 12.816±0.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PQ CIL_0007PQ_0002 VISTA 14:62762164-63363066
CIL_000919 CIL_000919_0002 VISTA 14:62906721-63507169
CIL_0008Y4 CIL_0008Y4_0002 VISTA 14:63067789-63669845
CIL_00051N CIL_00051N_0002 CGP 14:63122462-63177793

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005518 IEA collagen binding
GO:0005730 IEA nucleolus
GO:0005739 IDA mitochondrion
GO:0005764 IDA lysosome
GO:0008233 IEA peptidase activity
GO:0030574 IEA collagen catabolic process
GO:0030855 IEA epithelial cell differentiation
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043394 IEA proteoglycan binding
GO:0046697 IGI decidualization
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050790 IEA regulation of catalytic activity
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0097067 IEA cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055120 ctsba cathepsin B, a protein_coding Danio_rerio
ENSDARG00000067570 ctsbb capthepsin B, b protein_coding Danio_rerio
ENSG00000164733 CTSB cathepsin B protein_coding Homo_sapiens

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