C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: PDZ binding kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022612 Pbk-001 ENSMUSG00000022033 10090 + 14:65805837-65817822 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022612
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022612 1.861±1.66 0.741±0.25 0.543±0.23 8.649±7.49 0.433±0.12 1.988±1.24 0.114±0.03 0.198±0.08 11.092±10.13 0.609±0.00 0.057±0.03 3.364±1.72 11.005±3.75 17.560±6.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0002 VISTA 14:65449305-66050499

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0004674 ISO protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0018105 ISO peptidyl-serine phosphorylation
GO:0018107 ISO peptidyl-threonine phosphorylation
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032873 IMP negative regulation of stress-activated MAPK cascade
GO:0034644 IMP cellular response to UV
GO:0050728 IMP negative regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000301905 PBK-001 protein_coding Homo_sapiens 0 1090
ENST00000521226 PBK-005 nonsense_mediated_decay Homo_sapiens 0 604
ENST00000522944 PBK-002 protein_coding Homo_sapiens 0 719
ENST00000524266 PBK-006 nonsense_mediated_decay Homo_sapiens 0 592

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