C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dematin actin binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022099 Dmtn 10090 - 14:70602184-70636048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022694 Dmtn-201 70602184-70630154 protein_coding
  ENSMUST00000022695 Dmtn-202 70602185-70636048 protein_coding
  ENSMUST00000110984 Dmtn-203 70602185-70627065 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022694ENSMUST00000022695ENSMUST00000110984
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022694 1.396±0.66 1.181±0.07 N/A 1.781±0.00 1.610±0.00 0.692±0.39 0.254±0.02 12.108±9.37 14.863±13.49 0.843±0.00 0.040±0.00 0.363±0.12 1.685±0.00 0.482±0.12
ENSMUST00000022695 1.677±0.89 N/A N/A 10.945±8.77 1.682±0.40 N/A 0.217±0.00 7.561±0.93 5.199±4.36 0.914±0.00 0.117±0.05 N/A N/A 0.267±0.02
ENSMUST00000110984 N/A 1.049±0.00 0.611±0.00 9.591±0.00 N/A 0.503±0.00 0.632±0.00 N/A 30.648±17.07 N/A 0.038±0.00 0.779±0.00 1.386±0.88 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000812 CIL_000812_0002 VISTA 14:70334498-70935318
CIL_0008ZI CIL_0008ZI_0002 VISTA 14:70339990-70941193
CIL_000810 CIL_000810_0002 VISTA 14:70383794-70984839

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005102 ISS receptor binding
GO:0005515 IEA protein binding
GO:0005829 ISS cytosol
GO:0005884 ISS actin filament
GO:0005886 ISS plasma membrane
GO:0006461 IDA protein complex assembly
GO:0008360 ISS regulation of cell shape
GO:0010591 ISS regulation of lamellipodium assembly
GO:0010763 IDA positive regulation of fibroblast migration
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0010812 IMP negative regulation of cell-substrate adhesion
GO:0014731 ISS spectrin-associated cytoskeleton
GO:0016020 IDA membrane
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0030036 IMP actin cytoskeleton organization
GO:0030194 IMP positive regulation of blood coagulation
GO:0030507 ISS spectrin binding
GO:0030863 IDA cortical cytoskeleton
GO:0031095 ISS platelet dense tubular network membrane
GO:0031253 IDA cell projection membrane
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0035584 IMP calcium-mediated signaling using intracellular calcium source
GO:0035585 IMP calcium-mediated signaling using extracellular calcium source
GO:0043621 ISS protein self-association
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048821 IMP erythrocyte development
GO:0050732 IMP negative regulation of peptidyl-tyrosine phosphorylation
GO:0051017 ISS actin filament bundle assembly
GO:0051489 ISS regulation of filopodium assembly
GO:0051693 IEA actin filament capping
GO:0051895 IMP negative regulation of focal adhesion assembly
GO:0070560 IMP protein secretion by platelet
GO:0071277 IMP cellular response to calcium ion
GO:0071320 ISS cellular response to cAMP
GO:0090303 IMP positive regulation of wound healing
GO:0090315 IMP negative regulation of protein targeting to membrane
GO:0090527 IMP actin filament reorganization
GO:1900025 IMP negative regulation of substrate adhesion-dependent cell spreading
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading
GO:1901731 IMP positive regulation of platelet aggregation
GO:2001046 IMP positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013110 dmtn dematin actin binding protein protein_coding Danio_rerio
ENSG00000158856 DMTN dematin actin binding protein protein_coding Homo_sapiens

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