C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dematin actin binding protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022694 Dmtn-201 ENSMUSG00000022099 10090 - 14:70602184-70630154 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022694
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022694 1.396±0.66 1.181±0.07 1.781±0.00 1.610±0.00 0.692±0.39 0.254±0.02 12.108±9.37 14.863±13.49 0.843±0.00 0.040±0.00 0.363±0.12 1.685±0.00 0.482±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000812 CIL_000812_0002 VISTA 14:70334498-70935318
CIL_0008ZI CIL_0008ZI_0002 VISTA 14:70339990-70941193
CIL_000810 CIL_000810_0002 VISTA 14:70383794-70984839

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005102 ISS receptor binding
GO:0005829 ISS cytosol
GO:0005884 ISS actin filament
GO:0005886 ISS plasma membrane
GO:0006461 IDA protein complex assembly
GO:0008360 ISS regulation of cell shape
GO:0010591 ISS regulation of lamellipodium assembly
GO:0010763 IDA positive regulation of fibroblast migration
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0010812 IMP negative regulation of cell-substrate adhesion
GO:0014731 ISS spectrin-associated cytoskeleton
GO:0016020 IDA membrane
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0030036 IMP actin cytoskeleton organization
GO:0030194 IMP positive regulation of blood coagulation
GO:0030507 ISS spectrin binding
GO:0030863 IDA cortical cytoskeleton
GO:0031095 ISS platelet dense tubular network membrane
GO:0031253 IDA cell projection membrane
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0035584 IMP calcium-mediated signaling using intracellular calcium source
GO:0035585 IMP calcium-mediated signaling using extracellular calcium source
GO:0043621 ISS protein self-association
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048821 IMP erythrocyte development
GO:0050732 IMP negative regulation of peptidyl-tyrosine phosphorylation
GO:0051017 ISS actin filament bundle assembly
GO:0051489 ISS regulation of filopodium assembly
GO:0051693 IEA actin filament capping
GO:0051895 IMP negative regulation of focal adhesion assembly
GO:0070560 IMP protein secretion by platelet
GO:0071277 IMP cellular response to calcium ion
GO:0071320 ISS cellular response to cAMP
GO:0090303 IMP positive regulation of wound healing
GO:0090315 IMP negative regulation of protein targeting to membrane
GO:0090527 IMP actin filament reorganization
GO:1900025 IMP negative regulation of substrate adhesion-dependent cell spreading
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading
GO:1901731 IMP positive regulation of platelet aggregation
GO:2001046 IMP positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265800 DMTN-001 protein_coding Homo_sapiens 0 1264
ENST00000358242 DMTN-201 protein_coding Homo_sapiens 0 1253
ENST00000381470 DMTN-202 protein_coding Homo_sapiens 0 1478
ENST00000415253 DMTN-008 protein_coding Homo_sapiens 0 1463
ENST00000432128 DMTN-203 protein_coding Homo_sapiens 0 1238
ENST00000443491 DMTN-004 protein_coding Homo_sapiens 0 1332
ENST00000517305 DMTN-204 protein_coding Homo_sapiens 0 1253
ENST00000517418 DMTN-019 protein_coding Homo_sapiens 0 798
ENST00000517600 DMTN-007 protein_coding Homo_sapiens 0 861
ENST00000517804 DMTN-018 protein_coding Homo_sapiens 0 784
ENST00000518816 DMTN-005 retained_intron Homo_sapiens 0 268
ENST00000519333 DMTN-021 protein_coding Homo_sapiens 0 268
ENST00000519850 DMTN-015 protein_coding Homo_sapiens 0 442
ENST00000519907 DMTN-010 protein_coding Homo_sapiens 0 1478
ENST00000520174 DMTN-017 protein_coding Homo_sapiens 0 795
ENST00000520856 DMTN-006 retained_intron Homo_sapiens 0 399
ENST00000522148 DMTN-012 protein_coding Homo_sapiens 0 255
ENST00000522340 DMTN-022 protein_coding Homo_sapiens 0 318
ENST00000523266 DMTN-009 protein_coding Homo_sapiens 0 1264
ENST00000523300 DMTN-013 protein_coding Homo_sapiens 0 604
ENST00000523623 DMTN-016 protein_coding Homo_sapiens 0 545
ENST00000523782 DMTN-011 protein_coding Homo_sapiens 0 1332

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