C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glial cell line derived neurotrophic factor family receptor alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022103 Gfra2 10090 + 14:70890130-70979838 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022699 Gfra2-201 70890130-70979838 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022699 1.606±0.65 2.897±0.74 4.318±0.20 4.527±2.02 6.194±2.85 2.445±0.81 0.483±0.09 0.188±0.07 0.819±0.74 6.558±1.94 0.506±0.16 1.278±0.52 0.258±0.16 5.385±2.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000812 CIL_000812_0002 VISTA 14:70334498-70935318
CIL_0008ZI CIL_0008ZI_0002 VISTA 14:70339990-70941193
CIL_000810 CIL_000810_0002 VISTA 14:70383794-70984839

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005886 IEA plasma membrane
GO:0007169 IGI transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 IMP nervous system development
GO:0016167 IEA glial cell-derived neurotrophic factor receptor activity
GO:0031225 IEA anchored component of membrane
GO:0031953 IEA negative regulation of protein autophosphorylation
GO:0035860 IEA glial cell-derived neurotrophic factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042723 gfra2a glial cell line derived neurotrophic factor family receptor alpha 2a protein_coding Danio_rerio
ENSDARG00000044015 gfra2b glial cell line derived neurotrophic factor family receptor alpha 2b protein_coding Danio_rerio
ENSG00000168546 GFRA2 GDNF family receptor alpha 2 protein_coding Homo_sapiens

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