C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methyltransferase like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022160 Mettl3 10090 - 14:52294668-52305128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022767 Mettl3-001 52294841-52305128 protein_coding
  ENSMUST00000122962 Mettl3-004 52297205-52305086 nonsense_mediated_decay
  ENSMUST00000127797 Mettl3-006 52296989-52299776 retained_intron
  ENSMUST00000130550 Mettl3-008 52295707-52296762 retained_intron
  ENSMUST00000145875 Mettl3-007 52300356-52305099 nonsense_mediated_decay
  ENSMUST00000147768 Mettl3-002 52295507-52305124 nonsense_mediated_decay
  ENSMUST00000153539 Mettl3-003 52294668-52305083 nonsense_mediated_decay
  ENSMUST00000156611 Mettl3-005 52296661-52298456 retained_intron
  ENSMUST00000173138 Mettl3-015 52298025-52304987 nonsense_mediated_decay
  ENSMUST00000173546 Mettl3-010 52294857-52296669 retained_intron
  ENSMUST00000173656 Mettl3-011 52294857-52296752 protein_coding
  ENSMUST00000173896 Mettl3-014 52297470-52304987 nonsense_mediated_decay
  ENSMUST00000174351 Mettl3-012 52294849-52300348 nonsense_mediated_decay
  ENSMUST00000174360 Mettl3-013 52294857-52296751 protein_coding
  ENSMUST00000174853 Mettl3-009 52298035-52305107 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000022767
Transcript ID Adipose Bladder Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000022767 11.235±0.00 12.012±0.78 7.647±0.00 5.004±0.00 8.058±0.27 12.840±3.28 12.068±0.13 14.951±0.00 12.532±0.35 5.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CX CIL_0008CX_0002 VISTA 14:52247406-52849170
CIL_0005QL CIL_0005QL_0002 CGP 14:52261759-52296391
CIL_0002HL CIL_0002HL_0002 CGP 14:52279146-52305128
CIL_0002HK CIL_0002HK_0002 CGP 14:52294668-52328762

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001510 ISS RNA methylation
GO:0001734 ISO mRNA (N6-adenosine)-methyltransferase activity
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006397 IMP mRNA processing
GO:0007623 IMP circadian rhythm
GO:0016422 ISS mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
GO:0016556 ISO mRNA modification
GO:0016607 ISS nuclear speck
GO:0019827 IMP stem cell maintenance
GO:0036396 ISS MIS complex
GO:0061157 IMP mRNA destabilization
GO:0080009 IMP mRNA methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012827 mettl3 methyltransferase like 3 protein_coding Danio_rerio
ENSG00000165819 METTL3 methyltransferase like 3 protein_coding Homo_sapiens

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